Japan

Top 147 largest Japanese Companies in the Healthcare sector by Market Cap

This is the list of the largest public listed companies in the Healthcare sector from Japan by market capitalization with links to their reference stock and industry.

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Top Healthcare Companies from Japan as of Jan. 01, 2026

Rank Company Market Cap (USD) Country Sector Industry
1 Chugai Pharmaceutical Co. Ltd $87.94 B Japan Japanese Healthcare Japanese Drug Manufacturers—General
2 HOYA Corp $50.63 B Japan Japanese Healthcare Japanese Medical Instruments & Supplies
3 Daiichi Sankyo Company Ltd $45.64 B Japan Japanese Healthcare Japanese Drug Manufacturers—General
4 Takeda Pharmaceutical Company Limited $45.42 B Japan Japanese Healthcare Japanese Drug Manufacturers—Specialty & Generic
5 Otsuka Holdings Co. Ltd $29.81 B Japan Japanese Healthcare Japanese Drug Manufacturers—General
6 Terumo Corp $22.97 B Japan Japanese Healthcare Japanese Medical Instruments & Supplies
7 Astellas Pharma, Inc. $22.51 B Japan Japanese Healthcare Japanese Drug Manufacturers—General
8 Olympus Corp $14.76 B Japan Japanese Healthcare Japanese Medical Instruments & Supplies
9 Shionogi & Co. Ltd $14.56 B Japan Japanese Healthcare Japanese Drug Manufacturers—Specialty & Generic
10 M3, Inc. $11.14 B Japan Japanese Healthcare Japanese Health Information Services
11 Eisai Co. Ltd $8.82 B Japan Japanese Healthcare Japanese Drug Manufacturers—Specialty & Generic
12 Kyowa Kirin Co. Ltd $8.79 B Japan Japanese Healthcare Japanese Drug Manufacturers—General
13 Matsumotokiyoshi Holdings Co. Ltd $7.34 B Japan Japanese Healthcare Japanese Pharmaceutical Retailers
14 Sumitomo Dainippon Pharma Co. Ltd $6.92 B Japan Japanese Healthcare Japanese Drug Manufacturers—Specialty & Generic
15 Ono Pharmaceutical Co. Ltd $6.60 B Japan Japanese Healthcare Japanese Drug Manufacturers—General
16 Sysmex Corp $5.91 B Japan Japanese Healthcare Japanese Diagnostics & Research
17 Taisho Pharmaceutical Holdings Co. Ltd $5.07 B

(Jan. 1, 2024)

 Japan Japanese Healthcare Japanese Drug Manufacturers—Specialty & Generic
18 Asahi Intecc Co. Ltd $4.98 B Japan Japanese Healthcare Japanese Medical Instruments & Supplies
19 Tsuruha Holdings, Inc. $4.31 B Japan Japanese Healthcare Japanese Pharmaceutical Retailers
20 Sugi Holdings Co.,Ltd. $4.26 B Japan Japanese Healthcare Japanese Pharmaceutical Retailers
21 COSMOS Pharmaceutical Corp $3.78 B Japan Japanese Healthcare Japanese Pharmaceutical Retailers
22 Welcia Holdings Co. Ltd $3.61 B

(July 1, 2025)

 Japan Japanese Healthcare Japanese Pharmaceutical Retailers
23 MediPal Holdings Corp $3.56 B Japan Japanese Healthcare Japanese Medical Distribution
24 Santen Pharmaceutical Co. Ltd $3.29 B Japan Japanese Healthcare Japanese Drug Manufacturers—General
25 Sundrug Co.,Ltd. $3.23 B Japan Japanese Healthcare Japanese Pharmaceutical Retailers
26 Alfresa Holdings Corp $2.74 B Japan Japanese Healthcare Japanese Medical Distribution
27 Suzuken Co. Ltd $2.69 B Japan Japanese Healthcare Japanese Medical Distribution
28 Kusuri No Aoki Holdings Co. Ltd $2.43 B Japan Japanese Healthcare Japanese Pharmaceutical Retailers
29 cocokara fine, Inc. $2.21 B

(Sept. 1, 2021)

 Japan Japanese Healthcare Japanese Pharmaceutical Retailers
30 Toho Holdings Co. Ltd $1.95 B Japan Japanese Healthcare Japanese Drug Manufacturers—Specialty & Generic

Top Healthcare Companies from Japan as of Jan. 01, 2026

1. Chugai Pharmaceutical Co. Ltd

Company Profile: Chugai Pharmaceutical Co. Ltd
Market Cap (USD): $87.94 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Drug Manufacturers—General

2. HOYA Corp

Company Profile: HOYA Corp
Market Cap (USD): $50.63 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Medical Instruments & Supplies

3. Daiichi Sankyo Company Ltd

Company Profile: Daiichi Sankyo Company Ltd
Market Cap (USD): $45.64 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Drug Manufacturers—General

4. Takeda Pharmaceutical Company Limited

Company Profile: Takeda Pharmaceutical Company Limited
Market Cap (USD): $45.42 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Drug Manufacturers—Specialty & Generic

5. Otsuka Holdings Co. Ltd

Company Profile: Otsuka Holdings Co. Ltd
Market Cap (USD): $29.81 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Drug Manufacturers—General

6. Terumo Corp

Company Profile: Terumo Corp
Market Cap (USD): $22.97 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Medical Instruments & Supplies

7. Astellas Pharma, Inc.

Company Profile: Astellas Pharma, Inc.
Market Cap (USD): $22.51 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Drug Manufacturers—General

8. Olympus Corp

Company Profile: Olympus Corp
Market Cap (USD): $14.76 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Medical Instruments & Supplies

9. Shionogi & Co. Ltd

Company Profile: Shionogi & Co. Ltd
Market Cap (USD): $14.56 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Drug Manufacturers—Specialty & Generic

10. M3, Inc.

Company Profile: M3, Inc.
Market Cap (USD): $11.14 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Health Information Services

11. Eisai Co. Ltd

Company Profile: Eisai Co. Ltd
Market Cap (USD): $8.82 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Drug Manufacturers—Specialty & Generic

12. Kyowa Kirin Co. Ltd

Company Profile: Kyowa Kirin Co. Ltd
Market Cap (USD): $8.79 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Drug Manufacturers—General

13. Matsumotokiyoshi Holdings Co. Ltd

Company Profile: Matsumotokiyoshi Holdings Co. Ltd
Market Cap (USD): $7.34 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Pharmaceutical Retailers

14. Sumitomo Dainippon Pharma Co. Ltd

Company Profile: Sumitomo Dainippon Pharma Co. Ltd
Market Cap (USD): $6.92 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Drug Manufacturers—Specialty & Generic

15. Ono Pharmaceutical Co. Ltd

Company Profile: Ono Pharmaceutical Co. Ltd
Market Cap (USD): $6.60 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Drug Manufacturers—General

16. Sysmex Corp

Company Profile: Sysmex Corp
Market Cap (USD): $5.91 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Diagnostics & Research

17. Taisho Pharmaceutical Holdings Co. Ltd

Company Profile: Taisho Pharmaceutical Holdings Co. Ltd
Market Cap (USD): $5.07 B (Jan. 1, 2024)
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Drug Manufacturers—Specialty & Generic

18. Asahi Intecc Co. Ltd

Company Profile: Asahi Intecc Co. Ltd
Market Cap (USD): $4.98 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Medical Instruments & Supplies

19. Tsuruha Holdings, Inc.

Company Profile: Tsuruha Holdings, Inc.
Market Cap (USD): $4.31 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Pharmaceutical Retailers

20. Sugi Holdings Co.,Ltd.

Company Profile: Sugi Holdings Co.,Ltd.
Market Cap (USD): $4.26 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Pharmaceutical Retailers

21. COSMOS Pharmaceutical Corp

Company Profile: COSMOS Pharmaceutical Corp
Market Cap (USD): $3.78 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Pharmaceutical Retailers

22. Welcia Holdings Co. Ltd

Company Profile: Welcia Holdings Co. Ltd
Market Cap (USD): $3.61 B (July 1, 2025)
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Pharmaceutical Retailers

23. MediPal Holdings Corp

Company Profile: MediPal Holdings Corp
Market Cap (USD): $3.56 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Medical Distribution

24. Santen Pharmaceutical Co. Ltd

Company Profile: Santen Pharmaceutical Co. Ltd
Market Cap (USD): $3.29 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Drug Manufacturers—General

25. Sundrug Co.,Ltd.

Company Profile: Sundrug Co.,Ltd.
Market Cap (USD): $3.23 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Pharmaceutical Retailers

26. Alfresa Holdings Corp

Company Profile: Alfresa Holdings Corp
Market Cap (USD): $2.74 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Medical Distribution

27. Suzuken Co. Ltd

Company Profile: Suzuken Co. Ltd
Market Cap (USD): $2.69 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Medical Distribution

28. Kusuri No Aoki Holdings Co. Ltd

Company Profile: Kusuri No Aoki Holdings Co. Ltd
Market Cap (USD): $2.43 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Pharmaceutical Retailers

29. cocokara fine, Inc.

Company Profile: cocokara fine, Inc.
Market Cap (USD): $2.21 B (Sept. 1, 2021)
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Pharmaceutical Retailers

30. Toho Holdings Co. Ltd

Company Profile: Toho Holdings Co. Ltd
Market Cap (USD): $1.95 B
Country: Japan
Sector: Japanese Healthcare
Industry: Japanese Drug Manufacturers—Specialty & Generic

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