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Top NASDAQ Composite Companies by Market Cap and Stocks in 2026

This is the list of the largest public listed companies in the NASDAQ Composite index ranked by market capitalization, together with links to their reference stock, sector and industry.

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Top NASDAQ Composite Companies Ranking by Market Cap as of Jan. 1, 2026

Ranking Company Stock Market Cap (USD) Country Sector Industry
451 TG Therapeutics, Inc. TGTX $4.65 B United States US Healthcare US Biotechnology
452 Grand Canyon Education, Inc. LOPE $4.65 B United States US Consumer Staples US Education & Training Services
453 Global Blood Therapeutics, Inc. GBT $4.62 B

(Oct. 1, 2022)

 United States US Healthcare US Biotechnology
454 FormFactor, Inc. FORM $4.59 B United States US Technology US Semiconductors
455 Encore Wire Corporation WIRE $4.58 B

(July 1, 2024)

 United States US Industrials US Electrical Equipment & Parts
456 Lantheus Holdings, Inc. LNTH $4.57 B United States US Healthcare US Diagnostics & Research
457 Mercury Systems, Inc. MRCY $4.57 B United States US Industrials US Aerospace & Defense
458 Sanderson Farms, Inc. SAFM $4.55 B

(July 1, 2022)

 United States US Consumer Staples US Packaged Foods
459 Lancaster Colony Corporation LANC $4.54 B United States US Consumer Staples US Packaged Foods
460 Qurate Retail, Inc. QRTEA $4.54 B United States US Consumer Discretionary US Internet Retail
461 Qurate Retail, Inc. QRTEB $4.54 B United States US Consumer Discretionary US Internet Retail
462 Plains GP Holdings, L.P. PAGP $4.52 B United States US Energy US Oil & Gas Midstream
463 Avis Budget Group, Inc. CAR $4.51 B United States US Industrials US Rental & Leasing Services
464 Sunrun Inc. RUN $4.51 B United States US Technology US Solar
465 Akero Therapeutics, Inc. AKRO $4.50 B

(Dec. 1, 2025)

 United States US Healthcare US Biotechnology
466 Icahn Enterprises L.P. IEP $4.49 B United States US Industrials US Conglomerates
467 Upstart Holdings, Inc. UPST $4.46 B United States US Financials US Credit Services
468 ACADIA Pharmaceuticals Inc. ACAD $4.45 B United States US Healthcare US Biotechnology
469 Crinetics Pharmaceuticals, Inc. CRNX $4.43 B United States US Healthcare US Biotechnology
470 Hostess Brands, Inc. TWNK $4.43 B

(Nov. 1, 2023)

 United States US Consumer Staples US Packaged Foods
471 Enphase Energy, Inc. ENPH $4.42 B United States US Technology US Solar
472 Amicus Therapeutics, Inc. FOLD $4.41 B United States US Healthcare US Biotechnology
473 Silgan Holdings Inc. SLGN $4.41 B United States US Consumer Discretionary US Packaging & Containers
474 Akers Biosciences, Inc. AKER $4.41 B

(July 1, 2024)

 United States US Healthcare US Medical Instruments & Supplies
475 Syneos Health, Inc. SYNH $4.38 B

(July 1, 2023)

 United States US Healthcare US Diagnostics & Research
476 SSR Mining Inc. SSRM $4.38 B Canada Canadian Basic Materials Canadian Gold
477 Scholar Rock Holding Corporation SRRK $4.37 B United States US Healthcare US Biotechnology
478 OSI Systems, Inc. OSIS $4.34 B United States US Technology US Electronic Components
479 Silicon Laboratories Inc. SLAB $4.33 B United States US Technology US Semiconductors
480 Itron, Inc. ITRI $4.33 B United States US Technology US Scientific & Technical Instruments

Top NASDAQ Composite Companies Ranking by Market Cap as of Jan. 1, 2026

451. TG Therapeutics, Inc.

Company Profile: TG Therapeutics, Inc.
Market Cap (USD): $4.65 B
Stock: TGTX wb_incandescent
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

452. Grand Canyon Education, Inc.

Company Profile: Grand Canyon Education, Inc.
Market Cap (USD): $4.65 B
Stock: LOPE wb_incandescent
Country: United States
Sector: US Consumer Staples
Industry: US Education & Training Services

453. Global Blood Therapeutics, Inc.

Company Profile: Global Blood Therapeutics, Inc.
Market Cap (USD): $4.62 B (Oct. 1, 2022)
Stock: GBT wb_incandescent
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

454. FormFactor, Inc.

Company Profile: FormFactor, Inc.
Market Cap (USD): $4.59 B
Stock: FORM wb_incandescent
Country: United States
Sector: US Technology
Industry: US Semiconductors

455. Encore Wire Corporation

Company Profile: Encore Wire Corporation
Market Cap (USD): $4.58 B (July 1, 2024)
Stock: WIRE wb_incandescent
Country: United States
Sector: US Industrials
Industry: US Electrical Equipment & Parts

456. Lantheus Holdings, Inc.

Company Profile: Lantheus Holdings, Inc.
Market Cap (USD): $4.57 B
Stock: LNTH wb_incandescent
Country: United States
Sector: US Healthcare
Industry: US Diagnostics & Research

457. Mercury Systems, Inc.

Company Profile: Mercury Systems, Inc.
Market Cap (USD): $4.57 B
Stock: MRCY wb_incandescent
Country: United States
Sector: US Industrials
Industry: US Aerospace & Defense

458. Sanderson Farms, Inc.

Company Profile: Sanderson Farms, Inc.
Market Cap (USD): $4.55 B (July 1, 2022)
Stock: SAFM wb_incandescent
Country: United States
Sector: US Consumer Staples
Industry: US Packaged Foods

459. Lancaster Colony Corporation

Company Profile: Lancaster Colony Corporation
Market Cap (USD): $4.54 B
Stock: LANC wb_incandescent
Country: United States
Sector: US Consumer Staples
Industry: US Packaged Foods

460. Qurate Retail, Inc.

Company Profile: Qurate Retail, Inc.
Market Cap (USD): $4.54 B
Stock: QRTEA wb_incandescent
Country: United States
Sector: US Consumer Discretionary
Industry: US Internet Retail

461. Qurate Retail, Inc.

Company Profile: Qurate Retail, Inc.
Market Cap (USD): $4.54 B
Stock: QRTEB wb_incandescent
Country: United States
Sector: US Consumer Discretionary
Industry: US Internet Retail

462. Plains GP Holdings, L.P.

Company Profile: Plains GP Holdings, L.P.
Market Cap (USD): $4.52 B
Stock: PAGP wb_incandescent
Country: United States
Sector: US Energy
Industry: US Oil & Gas Midstream

463. Avis Budget Group, Inc.

Company Profile: Avis Budget Group, Inc.
Market Cap (USD): $4.51 B
Stock: CAR wb_incandescent
Country: United States
Sector: US Industrials
Industry: US Rental & Leasing Services

464. Sunrun Inc.

Company Profile: Sunrun Inc.
Market Cap (USD): $4.51 B
Stock: RUN wb_incandescent
Country: United States
Sector: US Technology
Industry: US Solar

465. Akero Therapeutics, Inc.

Company Profile: Akero Therapeutics, Inc.
Market Cap (USD): $4.50 B (Dec. 1, 2025)
Stock: AKRO wb_incandescent
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

466. Icahn Enterprises L.P.

Company Profile: Icahn Enterprises L.P.
Market Cap (USD): $4.49 B
Stock: IEP wb_incandescent
Country: United States
Sector: US Industrials
Industry: US Conglomerates

467. Upstart Holdings, Inc.

Company Profile: Upstart Holdings, Inc.
Market Cap (USD): $4.46 B
Stock: UPST wb_incandescent
Country: United States
Sector: US Financials
Industry: US Credit Services

468. ACADIA Pharmaceuticals Inc.

Company Profile: ACADIA Pharmaceuticals Inc.
Market Cap (USD): $4.45 B
Stock: ACAD wb_incandescent
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

469. Crinetics Pharmaceuticals, Inc.

Company Profile: Crinetics Pharmaceuticals, Inc.
Market Cap (USD): $4.43 B
Stock: CRNX wb_incandescent
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

470. Hostess Brands, Inc.

Company Profile: Hostess Brands, Inc.
Market Cap (USD): $4.43 B (Nov. 1, 2023)
Stock: TWNK wb_incandescent
Country: United States
Sector: US Consumer Staples
Industry: US Packaged Foods

471. Enphase Energy, Inc.

Company Profile: Enphase Energy, Inc.
Market Cap (USD): $4.42 B
Stock: ENPH wb_incandescent
Country: United States
Sector: US Technology
Industry: US Solar

472. Amicus Therapeutics, Inc.

Company Profile: Amicus Therapeutics, Inc.
Market Cap (USD): $4.41 B
Stock: FOLD wb_incandescent
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

473. Silgan Holdings Inc.

Company Profile: Silgan Holdings Inc.
Market Cap (USD): $4.41 B
Stock: SLGN wb_incandescent
Country: United States
Sector: US Consumer Discretionary
Industry: US Packaging & Containers

474. Akers Biosciences, Inc.

Company Profile: Akers Biosciences, Inc.
Market Cap (USD): $4.41 B (July 1, 2024)
Stock: AKER wb_incandescent
Country: United States
Sector: US Healthcare
Industry: US Medical Instruments & Supplies

475. Syneos Health, Inc.

Company Profile: Syneos Health, Inc.
Market Cap (USD): $4.38 B (July 1, 2023)
Stock: SYNH wb_incandescent
Country: United States
Sector: US Healthcare
Industry: US Diagnostics & Research

476. SSR Mining Inc.

Company Profile: SSR Mining Inc.
Market Cap (USD): $4.38 B
Stock: SSRM wb_incandescent
Country: Canada
Sector: Canadian Basic Materials
Industry: Canadian Gold

477. Scholar Rock Holding Corporation

Company Profile: Scholar Rock Holding Corporation
Market Cap (USD): $4.37 B
Stock: SRRK wb_incandescent
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

478. OSI Systems, Inc.

Company Profile: OSI Systems, Inc.
Market Cap (USD): $4.34 B
Stock: OSIS wb_incandescent
Country: United States
Sector: US Technology
Industry: US Electronic Components

479. Silicon Laboratories Inc.

Company Profile: Silicon Laboratories Inc.
Market Cap (USD): $4.33 B
Stock: SLAB wb_incandescent
Country: United States
Sector: US Technology
Industry: US Semiconductors

480. Itron, Inc.

Company Profile: Itron, Inc.
Market Cap (USD): $4.33 B
Stock: ITRI wb_incandescent
Country: United States
Sector: US Technology
Industry: US Scientific & Technical Instruments

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