Top 723 largest US Companies in the Biotechnology industry by Market Cap

This is the list of the largest public listed companies in the Biotechnology industry from the United States by market capitalization with links to their reference stock.

dashboard United States Biotechnology Industry Analysis
Top US Companies United States Analysis
language World Top Companies language World Companies Analysis

Browse Countries, Sectors, Industries, Stock Indices & Top Companies

Country / Territory

AND / OR

Sector / Industry

Stock Index

Top Biotechnology Companies from the United States as of Jan. 01, 2023

Ranking Company Market Cap (USD) Stock Country Sector Industry
1 Regeneron Pharmaceuticals, Inc. $79.53 B REGN United States Healthcare Biotechnology
2 Vertex Pharmaceuticals Incorporated $74.13 B VRTX United States Healthcare Biotechnology
3 Moderna, Inc. $68.42 B MRNA United States Healthcare Biotechnology
4 Alnylam Pharmaceuticals, Inc. $28.74 B ALNY United States Healthcare Biotechnology
5 Seagen Inc. $23.86 B SGEN United States Healthcare Biotechnology
6 BioMarin Pharmaceutical Inc. $19.86 B BMRN United States Healthcare Biotechnology
7 Viela Bio, Inc. $19.79 B VIE United States Healthcare Biotechnology
8 Incyte Corporation $17.83 B INCY United States Healthcare Biotechnology
9 Royalty Pharma plc $17.03 B RPRX United States Healthcare Biotechnology
10 Bio-Techne Corporation $12.94 B TECH United States Healthcare Biotechnology
11 United Therapeutics Corporation $12.43 B UTHR United States Healthcare Biotechnology
12 Neurocrine Biosciences, Inc. $11.82 B NBIX United States Healthcare Biotechnology
13 Sarepta Therapeutics, Inc. $10.68 B SRPT United States Healthcare Biotechnology
14 Acceleron Pharma Inc. $10.56 B

(Nov. 1, 2021)

 XLRN United States Healthcare Biotechnology
15 OncBioMune Pharmaceuticals, Inc. $8.67 B

(Feb. 1, 2022)

 OBMP United States Healthcare Biotechnology
16 Legend Biotech Corporation $8.04 B LEGN United States Healthcare Biotechnology
17 Halozyme Therapeutics, Inc. $7.33 B HALO United States Healthcare Biotechnology
18 Karuna Therapeutics, Inc. $6.73 B KRTX United States Healthcare Biotechnology
19 Arena Pharmaceuticals, Inc. $6.17 B

(March 1, 2022)

 ARNA United States Healthcare Biotechnology
20 Ionis Pharmaceuticals, Inc. $5.70 B IONS United States Healthcare Biotechnology
21 Exelixis, Inc. $5.35 B EXEL United States Healthcare Biotechnology
22 Madrigal Pharmaceuticals, Inc. $5.33 B MDGL United States Healthcare Biotechnology
23 Apellis Pharmaceuticals, Inc. $5.24 B APLS United States Healthcare Biotechnology
24 Intra-Cellular Therapies, Inc. $4.97 B ITCI United States Healthcare Biotechnology
25 Prometheus Biosciences, Inc. $4.95 B RXDX United States Healthcare Biotechnology
26 Cerevel Therapeutics Holdings, Inc. $4.66 B CERE United States Healthcare Biotechnology
27 Global Blood Therapeutics, Inc. $4.62 B

(Oct. 1, 2022)

 GBT United States Healthcare Biotechnology
28 Arrowhead Pharmaceuticals, Inc. $4.25 B ARWR United States Healthcare Biotechnology
29 Cytokinetics, Incorporated $4.02 B CYTK United States Healthcare Biotechnology
30 Denali Therapeutics Inc. $3.90 B DNLI United States Healthcare Biotechnology
31 Turning Point Therapeutics, Inc. $3.81 B

(Aug. 1, 2022)

 TPTX United States Healthcare Biotechnology
32 ChemoCentryx, Inc. $3.74 B

(Oct. 1, 2022)

 CCXI United States Healthcare Biotechnology
33 Vaxcyte, Inc. $3.63 B PCVX United States Healthcare Biotechnology
34 NantKwest, Inc. $3.39 B NK United States Healthcare Biotechnology
35 Maravai LifeSciences Holdings, Inc. $3.39 B MRVI United States Healthcare Biotechnology
36 Intellia Therapeutics, Inc. $3.35 B NTLA United States Healthcare Biotechnology
37 Vir Biotechnology, Inc. $3.34 B VIR United States Healthcare Biotechnology
38 Amicus Therapeutics, Inc. $3.33 B FOLD United States Healthcare Biotechnology
39 Ultragenyx Pharmaceutical Inc. $3.31 B RARE United States Healthcare Biotechnology
40 Harmony Biosciences Holdings, Inc. $3.20 B HRMY United States Healthcare Biotechnology
41 VitaSpring Biomedical Co. Ltd $2.97 B VSBC United States Healthcare Biotechnology
42 Dicerna Pharmaceuticals, Inc. $2.93 B

(Dec. 1, 2021)

 DRNA United States Healthcare Biotechnology
43 Beam Therapeutics Inc. $2.90 B BEAM United States Healthcare Biotechnology
44 PTC Therapeutics, Inc. $2.88 B PTCT United States Healthcare Biotechnology
45 Translate Bio, Inc. $2.84 B

(Aug. 1, 2021)

 TBIO United States Healthcare Biotechnology
46 Blueprint Medicines Corporation $2.81 B BPMC United States Healthcare Biotechnology
47 ACADIA Pharmaceuticals Inc. $2.77 B ACAD United States Healthcare Biotechnology
48 Axsome Therapeutics, Inc. $2.75 B AXSM United States Healthcare Biotechnology
49 Mirati Therapeutics, Inc. $2.70 B MRTX United States Healthcare Biotechnology
50 Insmed Incorporated $2.67 B INSM United States Healthcare Biotechnology

Top Biotechnology Companies from the United States as of Jan. 01, 2023

1. Regeneron Pharmaceuticals, Inc.

Market Cap (USD): $79.53 B

Stock: REGN

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Regeneron Pharmaceuticals, Inc. Company Profile

2. Vertex Pharmaceuticals Incorporated

Market Cap (USD): $74.13 B

Stock: VRTX

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Vertex Pharmaceuticals Incorporated Company Profile

3. Moderna, Inc.

Market Cap (USD): $68.42 B

Stock: MRNA

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Moderna, Inc. Company Profile

4. Alnylam Pharmaceuticals, Inc.

Market Cap (USD): $28.74 B

Stock: ALNY

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Alnylam Pharmaceuticals, Inc. Company Profile

5. Seagen Inc.

Market Cap (USD): $23.86 B

Stock: SGEN

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Seagen Inc. Company Profile

6. BioMarin Pharmaceutical Inc.

Market Cap (USD): $19.86 B

Stock: BMRN

Country: United States

Sector: Healthcare

Industry: Biotechnology

business BioMarin Pharmaceutical Inc. Company Profile

7. Viela Bio, Inc.

Market Cap (USD): $19.79 B

Stock: VIE

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Viela Bio, Inc. Company Profile

8. Incyte Corporation

Market Cap (USD): $17.83 B

Stock: INCY

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Incyte Corporation Company Profile

9. Royalty Pharma plc

Market Cap (USD): $17.03 B

Stock: RPRX

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Royalty Pharma plc Company Profile

10. Bio-Techne Corporation

Market Cap (USD): $12.94 B

Stock: TECH

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Bio-Techne Corporation Company Profile

11. United Therapeutics Corporation

Market Cap (USD): $12.43 B

Stock: UTHR

Country: United States

Sector: Healthcare

Industry: Biotechnology

business United Therapeutics Corporation Company Profile

12. Neurocrine Biosciences, Inc.

Market Cap (USD): $11.82 B

Stock: NBIX

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Neurocrine Biosciences, Inc. Company Profile

13. Sarepta Therapeutics, Inc.

Market Cap (USD): $10.68 B

Stock: SRPT

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Sarepta Therapeutics, Inc. Company Profile

14. Acceleron Pharma Inc.

Market Cap (USD): $10.56 B

(Nov. 1, 2021)

Stock: XLRN

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Acceleron Pharma Inc. Company Profile

15. OncBioMune Pharmaceuticals, Inc.

Market Cap (USD): $8.67 B

(Feb. 1, 2022)

Stock: OBMP

Country: United States

Sector: Healthcare

Industry: Biotechnology

business OncBioMune Pharmaceuticals, Inc. Company Profile

16. Legend Biotech Corporation

Market Cap (USD): $8.04 B

Stock: LEGN

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Legend Biotech Corporation Company Profile

17. Halozyme Therapeutics, Inc.

Market Cap (USD): $7.33 B

Stock: HALO

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Halozyme Therapeutics, Inc. Company Profile

18. Karuna Therapeutics, Inc.

Market Cap (USD): $6.73 B

Stock: KRTX

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Karuna Therapeutics, Inc. Company Profile

19. Arena Pharmaceuticals, Inc.

Market Cap (USD): $6.17 B

(March 1, 2022)

Stock: ARNA

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Arena Pharmaceuticals, Inc. Company Profile

20. Ionis Pharmaceuticals, Inc.

Market Cap (USD): $5.70 B

Stock: IONS

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Ionis Pharmaceuticals, Inc. Company Profile

21. Exelixis, Inc.

Market Cap (USD): $5.35 B

Stock: EXEL

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Exelixis, Inc. Company Profile

22. Madrigal Pharmaceuticals, Inc.

Market Cap (USD): $5.33 B

Stock: MDGL

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Madrigal Pharmaceuticals, Inc. Company Profile

23. Apellis Pharmaceuticals, Inc.

Market Cap (USD): $5.24 B

Stock: APLS

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Apellis Pharmaceuticals, Inc. Company Profile

24. Intra-Cellular Therapies, Inc.

Market Cap (USD): $4.97 B

Stock: ITCI

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Intra-Cellular Therapies, Inc. Company Profile

25. Prometheus Biosciences, Inc.

Market Cap (USD): $4.95 B

Stock: RXDX

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Prometheus Biosciences, Inc. Company Profile

26. Cerevel Therapeutics Holdings, Inc.

Market Cap (USD): $4.66 B

Stock: CERE

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Cerevel Therapeutics Holdings, Inc. Company Profile

27. Global Blood Therapeutics, Inc.

Market Cap (USD): $4.62 B

(Oct. 1, 2022)

Stock: GBT

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Global Blood Therapeutics, Inc. Company Profile

28. Arrowhead Pharmaceuticals, Inc.

Market Cap (USD): $4.25 B

Stock: ARWR

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Arrowhead Pharmaceuticals, Inc. Company Profile

29. Cytokinetics, Incorporated

Market Cap (USD): $4.02 B

Stock: CYTK

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Cytokinetics, Incorporated Company Profile

30. Denali Therapeutics Inc.

Market Cap (USD): $3.90 B

Stock: DNLI

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Denali Therapeutics Inc. Company Profile

31. Turning Point Therapeutics, Inc.

Market Cap (USD): $3.81 B

(Aug. 1, 2022)

Stock: TPTX

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Turning Point Therapeutics, Inc. Company Profile

32. ChemoCentryx, Inc.

Market Cap (USD): $3.74 B

(Oct. 1, 2022)

Stock: CCXI

Country: United States

Sector: Healthcare

Industry: Biotechnology

business ChemoCentryx, Inc. Company Profile

33. Vaxcyte, Inc.

Market Cap (USD): $3.63 B

Stock: PCVX

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Vaxcyte, Inc. Company Profile

34. NantKwest, Inc.

Market Cap (USD): $3.39 B

Stock: NK

Country: United States

Sector: Healthcare

Industry: Biotechnology

business NantKwest, Inc. Company Profile

35. Maravai LifeSciences Holdings, Inc.

Market Cap (USD): $3.39 B

Stock: MRVI

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Maravai LifeSciences Holdings, Inc. Company Profile

36. Intellia Therapeutics, Inc.

Market Cap (USD): $3.35 B

Stock: NTLA

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Intellia Therapeutics, Inc. Company Profile

37. Vir Biotechnology, Inc.

Market Cap (USD): $3.34 B

Stock: VIR

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Vir Biotechnology, Inc. Company Profile

38. Amicus Therapeutics, Inc.

Market Cap (USD): $3.33 B

Stock: FOLD

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Amicus Therapeutics, Inc. Company Profile

39. Ultragenyx Pharmaceutical Inc.

Market Cap (USD): $3.31 B

Stock: RARE

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Ultragenyx Pharmaceutical Inc. Company Profile

40. Harmony Biosciences Holdings, Inc.

Market Cap (USD): $3.20 B

Stock: HRMY

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Harmony Biosciences Holdings, Inc. Company Profile

41. VitaSpring Biomedical Co. Ltd

Market Cap (USD): $2.97 B

Stock: VSBC

Country: United States

Sector: Healthcare

Industry: Biotechnology

business VitaSpring Biomedical Co. Ltd Company Profile

42. Dicerna Pharmaceuticals, Inc.

Market Cap (USD): $2.93 B

(Dec. 1, 2021)

Stock: DRNA

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Dicerna Pharmaceuticals, Inc. Company Profile

43. Beam Therapeutics Inc.

Market Cap (USD): $2.90 B

Stock: BEAM

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Beam Therapeutics Inc. Company Profile

44. PTC Therapeutics, Inc.

Market Cap (USD): $2.88 B

Stock: PTCT

Country: United States

Sector: Healthcare

Industry: Biotechnology

business PTC Therapeutics, Inc. Company Profile

45. Translate Bio, Inc.

Market Cap (USD): $2.84 B

(Aug. 1, 2021)

Stock: TBIO

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Translate Bio, Inc. Company Profile

46. Blueprint Medicines Corporation

Market Cap (USD): $2.81 B

Stock: BPMC

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Blueprint Medicines Corporation Company Profile

47. ACADIA Pharmaceuticals Inc.

Market Cap (USD): $2.77 B

Stock: ACAD

Country: United States

Sector: Healthcare

Industry: Biotechnology

business ACADIA Pharmaceuticals Inc. Company Profile

48. Axsome Therapeutics, Inc.

Market Cap (USD): $2.75 B

Stock: AXSM

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Axsome Therapeutics, Inc. Company Profile

49. Mirati Therapeutics, Inc.

Market Cap (USD): $2.70 B

Stock: MRTX

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Mirati Therapeutics, Inc. Company Profile

50. Insmed Incorporated

Market Cap (USD): $2.67 B

Stock: INSM

Country: United States

Sector: Healthcare

Industry: Biotechnology

business Insmed Incorporated Company Profile

Companies in key countries

format_list_bulleted All Countries

Companies in key stock indices

US companies in key sectors

dashboard US Market Analysis