United States

Top 538 largest US Companies in the Biotechnology industry by Market Cap

This is the list of the largest public listed companies in the Biotechnology industry from the United States by market capitalization with links to their reference stock.

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Top Biotechnology Companies from the United States as of Jul. 01, 2025

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Rank Company Market Cap (USD) Country Sector Industry
61 CymaBay Therapeutics, Inc. $2.61 B

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology
62 IVERIC bio, Inc. $2.52 B

(Jan. 1, 2023)

 United States US Healthcare US Biotechnology
63 Mirum Pharmaceuticals, Inc. $2.49 B United States US Healthcare US Biotechnology
64 ImmunityBio, Inc. $2.33 B United States US Healthcare US Biotechnology
65 Arrowhead Pharmaceuticals, Inc. $2.32 B United States US Healthcare US Biotechnology
66 Apellis Pharmaceuticals, Inc. $2.29 B United States US Healthcare US Biotechnology
67 Deciphera Pharmaceuticals, Inc. $2.21 B

(June 1, 2024)

 United States US Healthcare US Biotechnology
68 Ligand Pharmaceuticals Incorporated $2.21 B United States US Healthcare US Biotechnology
69 Veracyte, Inc. $2.15 B United States US Healthcare US Biotechnology
70 Recursion Pharmaceuticals, Inc. $2.14 B United States US Healthcare US Biotechnology
71 Denali Therapeutics Inc. $2.13 B United States US Healthcare US Biotechnology
72 Agios Pharmaceuticals, Inc. $2.09 B United States US Healthcare US Biotechnology
73 Vericel Corporation $2.09 B United States US Healthcare US Biotechnology
74 Beam Therapeutics Inc. $2.01 B United States US Healthcare US Biotechnology
75 IDEAYA Biosciences, Inc. $1.92 B United States US Healthcare US Biotechnology
76 BioCryst Pharmaceuticals, Inc. $1.87 B United States US Healthcare US Biotechnology
77 Harmony Biosciences Holdings, Inc. $1.84 B United States US Healthcare US Biotechnology
78 Certara, Inc. $1.84 B United States US Healthcare US Biotechnology
79 Amicus Therapeutics, Inc. $1.83 B United States US Healthcare US Biotechnology
80 Adaptive Biotechnologies Corporation $1.79 B United States US Healthcare US Biotechnology
81 Sarepta Therapeutics, Inc. $1.79 B United States US Healthcare US Biotechnology
82 Tarsus Pharmaceuticals, Inc. $1.73 B United States US Healthcare US Biotechnology
83 Biohaven Pharmaceutical Holding Company Ltd. $1.68 B

(July 1, 2023)

 United States US Healthcare US Biotechnology
84 Arcutis Biotherapeutics, Inc. $1.65 B United States US Healthcare US Biotechnology
85 Kadmon Holdings, Inc. $1.63 B

(Nov. 1, 2021)

 United States US Healthcare US Biotechnology
86 Morphic Holding, Inc. $1.59 B

(July 1, 2024)

 United States US Healthcare US Biotechnology
87 Ocular Therapeutix, Inc. $1.53 B United States US Healthcare US Biotechnology
88 Vera Therapeutics, Inc. $1.51 B United States US Healthcare US Biotechnology
89 Zogenix, Inc. $1.49 B

(March 1, 2022)

 United States US Healthcare US Biotechnology
90 89bio, Inc. $1.48 B United States US Healthcare US Biotechnology

Top Biotechnology Companies from the United States as of Jul. 01, 2025

61. CymaBay Therapeutics, Inc.

Company Profile: CymaBay Therapeutics, Inc.
Market Cap (USD): $2.61 B (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

62. IVERIC bio, Inc.

Company Profile: IVERIC bio, Inc.
Market Cap (USD): $2.52 B (Jan. 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

63. Mirum Pharmaceuticals, Inc.

Company Profile: Mirum Pharmaceuticals, Inc.
Market Cap (USD): $2.49 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

64. ImmunityBio, Inc.

Company Profile: ImmunityBio, Inc.
Market Cap (USD): $2.33 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

65. Arrowhead Pharmaceuticals, Inc.

Company Profile: Arrowhead Pharmaceuticals, Inc.
Market Cap (USD): $2.32 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

66. Apellis Pharmaceuticals, Inc.

Company Profile: Apellis Pharmaceuticals, Inc.
Market Cap (USD): $2.29 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

67. Deciphera Pharmaceuticals, Inc.

Company Profile: Deciphera Pharmaceuticals, Inc.
Market Cap (USD): $2.21 B (June 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

68. Ligand Pharmaceuticals Incorporated

Company Profile: Ligand Pharmaceuticals Incorporated
Market Cap (USD): $2.21 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

69. Veracyte, Inc.

Company Profile: Veracyte, Inc.
Market Cap (USD): $2.15 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

70. Recursion Pharmaceuticals, Inc.

Company Profile: Recursion Pharmaceuticals, Inc.
Market Cap (USD): $2.14 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

71. Denali Therapeutics Inc.

Company Profile: Denali Therapeutics Inc.
Market Cap (USD): $2.13 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

72. Agios Pharmaceuticals, Inc.

Company Profile: Agios Pharmaceuticals, Inc.
Market Cap (USD): $2.09 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

73. Vericel Corporation

Company Profile: Vericel Corporation
Market Cap (USD): $2.09 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

74. Beam Therapeutics Inc.

Company Profile: Beam Therapeutics Inc.
Market Cap (USD): $2.01 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

75. IDEAYA Biosciences, Inc.

Company Profile: IDEAYA Biosciences, Inc.
Market Cap (USD): $1.92 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

76. BioCryst Pharmaceuticals, Inc.

Company Profile: BioCryst Pharmaceuticals, Inc.
Market Cap (USD): $1.87 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

77. Harmony Biosciences Holdings, Inc.

Company Profile: Harmony Biosciences Holdings, Inc.
Market Cap (USD): $1.84 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

78. Certara, Inc.

Company Profile: Certara, Inc.
Market Cap (USD): $1.84 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

79. Amicus Therapeutics, Inc.

Company Profile: Amicus Therapeutics, Inc.
Market Cap (USD): $1.83 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

80. Adaptive Biotechnologies Corporation

Company Profile: Adaptive Biotechnologies Corporation
Market Cap (USD): $1.79 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

81. Sarepta Therapeutics, Inc.

Company Profile: Sarepta Therapeutics, Inc.
Market Cap (USD): $1.79 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

82. Tarsus Pharmaceuticals, Inc.

Company Profile: Tarsus Pharmaceuticals, Inc.
Market Cap (USD): $1.73 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

83. Biohaven Pharmaceutical Holding Company Ltd.

Company Profile: Biohaven Pharmaceutical Holding Company Ltd.
Market Cap (USD): $1.68 B (July 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

84. Arcutis Biotherapeutics, Inc.

Company Profile: Arcutis Biotherapeutics, Inc.
Market Cap (USD): $1.65 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

85. Kadmon Holdings, Inc.

Company Profile: Kadmon Holdings, Inc.
Market Cap (USD): $1.63 B (Nov. 1, 2021)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

86. Morphic Holding, Inc.

Company Profile: Morphic Holding, Inc.
Market Cap (USD): $1.59 B (July 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

87. Ocular Therapeutix, Inc.

Company Profile: Ocular Therapeutix, Inc.
Market Cap (USD): $1.53 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

88. Vera Therapeutics, Inc.

Company Profile: Vera Therapeutics, Inc.
Market Cap (USD): $1.51 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

89. Zogenix, Inc.

Company Profile: Zogenix, Inc.
Market Cap (USD): $1.49 B (March 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

90. 89bio, Inc.

Company Profile: 89bio, Inc.
Market Cap (USD): $1.48 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

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