United States

Top 538 largest US Companies in the Biotechnology industry by Market Cap

This is the list of the largest public listed companies in the Biotechnology industry from the United States by market capitalization with links to their reference stock.

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Top Biotechnology Companies from the United States as of Jan. 01, 2026

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Rank Company Market Cap (USD) Country Sector Industry
61 ChemoCentryx, Inc. $3.74 B

(Oct. 1, 2022)

 United States US Healthcare US Biotechnology
62 Arcutis Biotherapeutics, Inc. $3.55 B United States US Healthcare US Biotechnology
63 SpringWorks Therapeutics, Inc. $3.54 B

(July 1, 2025)

 United States US Healthcare US Biotechnology
64 Travere Therapeutics Inc. $3.54 B United States US Healthcare US Biotechnology
65 Vera Therapeutics, Inc. $3.45 B United States US Healthcare US Biotechnology
66 Tarsus Pharmaceuticals, Inc. $3.43 B United States US Healthcare US Biotechnology
67 Veracyte, Inc. $3.35 B United States US Healthcare US Biotechnology
68 Apellis Pharmaceuticals, Inc. $3.27 B United States US Healthcare US Biotechnology
69 Liquidia Corp $3.06 B United States US Healthcare US Biotechnology
70 Dyne Therapeutics, Inc. $3.05 B United States US Healthcare US Biotechnology
71 IDEAYA Biosciences, Inc. $2.97 B United States US Healthcare US Biotechnology
72 Nuvation Bio, Inc. $2.94 B United States US Healthcare US Biotechnology
73 Dicerna Pharmaceuticals, Inc. $2.93 B

(Dec. 1, 2021)

 United States US Healthcare US Biotechnology
74 Viridian Therapeutics, Inc. $2.93 B United States US Healthcare US Biotechnology
75 Arcus Biosciences, Inc. $2.88 B United States US Healthcare US Biotechnology
76 Catalyst Pharmaceuticals, Inc. $2.85 B United States US Healthcare US Biotechnology
77 Beam Therapeutics Inc. $2.75 B United States US Healthcare US Biotechnology
78 Liquidia Corporation $2.73 B United States US Healthcare US Biotechnology
79 Chinook Therapeutics, Inc. $2.62 B

(July 1, 2023)

 United States US Healthcare US Biotechnology
80 CymaBay Therapeutics, Inc. $2.61 B

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology
81 Denali Therapeutics Inc. $2.54 B United States US Healthcare US Biotechnology
82 IVERIC bio, Inc. $2.52 B

(Jan. 1, 2023)

 United States US Healthcare US Biotechnology
83 Ocular Therapeutix, Inc. $2.52 B United States US Healthcare US Biotechnology
84 Edgewise Therapeutics, Inc. $2.51 B United States US Healthcare US Biotechnology
85 Adaptive Biotechnologies Corporation $2.43 B United States US Healthcare US Biotechnology
86 NantKwest, Inc. $2.38 B United States US Healthcare US Biotechnology
87 Immunome, Inc. $2.30 B United States US Healthcare US Biotechnology
88 Ultragenyx Pharmaceutical Inc. $2.28 B United States US Healthcare US Biotechnology
89 Sarepta Therapeutics, Inc. $2.23 B United States US Healthcare US Biotechnology
90 Deciphera Pharmaceuticals, Inc. $2.21 B

(June 1, 2024)

 United States US Healthcare US Biotechnology

Top Biotechnology Companies from the United States as of Jan. 01, 2026

61. ChemoCentryx, Inc.

Company Profile: ChemoCentryx, Inc.
Market Cap (USD): $3.74 B (Oct. 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

62. Arcutis Biotherapeutics, Inc.

Company Profile: Arcutis Biotherapeutics, Inc.
Market Cap (USD): $3.55 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

63. SpringWorks Therapeutics, Inc.

Company Profile: SpringWorks Therapeutics, Inc.
Market Cap (USD): $3.54 B (July 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

64. Travere Therapeutics Inc.

Company Profile: Travere Therapeutics Inc.
Market Cap (USD): $3.54 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

65. Vera Therapeutics, Inc.

Company Profile: Vera Therapeutics, Inc.
Market Cap (USD): $3.45 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

66. Tarsus Pharmaceuticals, Inc.

Company Profile: Tarsus Pharmaceuticals, Inc.
Market Cap (USD): $3.43 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

67. Veracyte, Inc.

Company Profile: Veracyte, Inc.
Market Cap (USD): $3.35 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

68. Apellis Pharmaceuticals, Inc.

Company Profile: Apellis Pharmaceuticals, Inc.
Market Cap (USD): $3.27 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

69. Liquidia Corp

Company Profile: Liquidia Corp
Market Cap (USD): $3.06 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

70. Dyne Therapeutics, Inc.

Company Profile: Dyne Therapeutics, Inc.
Market Cap (USD): $3.05 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

71. IDEAYA Biosciences, Inc.

Company Profile: IDEAYA Biosciences, Inc.
Market Cap (USD): $2.97 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

72. Nuvation Bio, Inc.

Company Profile: Nuvation Bio, Inc.
Market Cap (USD): $2.94 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

73. Dicerna Pharmaceuticals, Inc.

Company Profile: Dicerna Pharmaceuticals, Inc.
Market Cap (USD): $2.93 B (Dec. 1, 2021)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

74. Viridian Therapeutics, Inc.

Company Profile: Viridian Therapeutics, Inc.
Market Cap (USD): $2.93 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

75. Arcus Biosciences, Inc.

Company Profile: Arcus Biosciences, Inc.
Market Cap (USD): $2.88 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

76. Catalyst Pharmaceuticals, Inc.

Company Profile: Catalyst Pharmaceuticals, Inc.
Market Cap (USD): $2.85 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

77. Beam Therapeutics Inc.

Company Profile: Beam Therapeutics Inc.
Market Cap (USD): $2.75 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

78. Liquidia Corporation

Company Profile: Liquidia Corporation
Market Cap (USD): $2.73 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

79. Chinook Therapeutics, Inc.

Company Profile: Chinook Therapeutics, Inc.
Market Cap (USD): $2.62 B (July 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

80. CymaBay Therapeutics, Inc.

Company Profile: CymaBay Therapeutics, Inc.
Market Cap (USD): $2.61 B (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

81. Denali Therapeutics Inc.

Company Profile: Denali Therapeutics Inc.
Market Cap (USD): $2.54 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

82. IVERIC bio, Inc.

Company Profile: IVERIC bio, Inc.
Market Cap (USD): $2.52 B (Jan. 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

83. Ocular Therapeutix, Inc.

Company Profile: Ocular Therapeutix, Inc.
Market Cap (USD): $2.52 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

84. Edgewise Therapeutics, Inc.

Company Profile: Edgewise Therapeutics, Inc.
Market Cap (USD): $2.51 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

85. Adaptive Biotechnologies Corporation

Company Profile: Adaptive Biotechnologies Corporation
Market Cap (USD): $2.43 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

86. NantKwest, Inc.

Company Profile: NantKwest, Inc.
Market Cap (USD): $2.38 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

87. Immunome, Inc.

Company Profile: Immunome, Inc.
Market Cap (USD): $2.30 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

88. Ultragenyx Pharmaceutical Inc.

Company Profile: Ultragenyx Pharmaceutical Inc.
Market Cap (USD): $2.28 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

89. Sarepta Therapeutics, Inc.

Company Profile: Sarepta Therapeutics, Inc.
Market Cap (USD): $2.23 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

90. Deciphera Pharmaceuticals, Inc.

Company Profile: Deciphera Pharmaceuticals, Inc.
Market Cap (USD): $2.21 B (June 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

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