United States

Top 538 largest US Companies in the Biotechnology industry by Market Cap

This is the list of the largest public listed companies in the Biotechnology industry from the United States by market capitalization with links to their reference stock.

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Top Biotechnology Companies from the United States as of Jul. 01, 2025

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Rank Company Market Cap (USD) Country Sector Industry
151 Sage Therapeutics, Inc. $576.1 M United States US Healthcare US Biotechnology
152 Keros Therapeutics, Inc. $546.3 M United States US Healthcare US Biotechnology
153 AVEO Pharmaceuticals, Inc. $521.4 M

(Jan. 1, 2023)

 United States US Healthcare US Biotechnology
154 Kura Oncology, Inc. $507.3 M United States US Healthcare US Biotechnology
155 Akouos, Inc. $491.0 M

(Nov. 1, 2022)

 United States US Healthcare US Biotechnology
156 Precigen, Inc. $478.2 M United States US Healthcare US Biotechnology
157 SIGA Technologies, Inc. $477.9 M United States US Healthcare US Biotechnology
158 Capricor Therapeutics, Inc. $468.5 M United States US Healthcare US Biotechnology
159 Cullinan Management, Inc. $460.9 M United States US Healthcare US Biotechnology
160 REGENXBIO Inc. $440.4 M United States US Healthcare US Biotechnology
161 Gemini Therapeutics, Inc. $438.8 M United States US Healthcare US Biotechnology
162 PureTech Health plc $432.7 M United States US Healthcare US Biotechnology
163 Concert Pharmaceuticals, Inc. $401.9 M

(June 1, 2024)

 United States US Healthcare US Biotechnology
164 CytomX Therapeutics, Inc. $393.9 M United States US Healthcare US Biotechnology
165 iTeos Therapeutics, Inc. $389.6 M United States US Healthcare US Biotechnology
166 Eton Pharmaceuticals, Inc. $387.5 M United States US Healthcare US Biotechnology
167 Altimmune, Inc. $386.1 M United States US Healthcare US Biotechnology
168 Compass Therapeutics, Inc. $384.4 M United States US Healthcare US Biotechnology
169 Revance Therapeutics, Inc. $381.0 M

(Jan. 1, 2025)

 United States US Healthcare US Biotechnology
170 Savara Inc. $378.5 M United States US Healthcare US Biotechnology
171 Terns Pharmaceuticals, Inc. $377.3 M United States US Healthcare US Biotechnology
172 Arcturus Therapeutics Holdings Inc. $373.7 M United States US Healthcare US Biotechnology
173 Fulcrum Therapeutics, Inc. $373.5 M United States US Healthcare US Biotechnology
174 Aquestive Therapeutics, Inc. $369.5 M United States US Healthcare US Biotechnology
175 Northwest Biotherapeutics, Inc. $359.4 M United States US Healthcare US Biotechnology
176 Chimerix, Inc. $356.3 M

(Jan. 1, 2025)

 United States US Healthcare US Biotechnology
177 CytoDyn, Inc. $351.2 M United States US Healthcare US Biotechnology
178 Silverback Therapeutics, Inc. $341.8 M

(July 1, 2024)

 United States US Healthcare US Biotechnology
179 Rigel Pharmaceuticals, Inc. $338.3 M United States US Healthcare US Biotechnology
180 Heron Therapeutics, Inc. $335.6 M United States US Healthcare US Biotechnology

Top Biotechnology Companies from the United States as of Jul. 01, 2025

151. Sage Therapeutics, Inc.

Company Profile: Sage Therapeutics, Inc.
Market Cap (USD): $576.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

152. Keros Therapeutics, Inc.

Company Profile: Keros Therapeutics, Inc.
Market Cap (USD): $546.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

153. AVEO Pharmaceuticals, Inc.

Company Profile: AVEO Pharmaceuticals, Inc.
Market Cap (USD): $521.4 M (Jan. 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

154. Kura Oncology, Inc.

Company Profile: Kura Oncology, Inc.
Market Cap (USD): $507.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

155. Akouos, Inc.

Company Profile: Akouos, Inc.
Market Cap (USD): $491.0 M (Nov. 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

156. Precigen, Inc.

Company Profile: Precigen, Inc.
Market Cap (USD): $478.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

157. SIGA Technologies, Inc.

Company Profile: SIGA Technologies, Inc.
Market Cap (USD): $477.9 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

158. Capricor Therapeutics, Inc.

Company Profile: Capricor Therapeutics, Inc.
Market Cap (USD): $468.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

159. Cullinan Management, Inc.

Company Profile: Cullinan Management, Inc.
Market Cap (USD): $460.9 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

160. REGENXBIO Inc.

Company Profile: REGENXBIO Inc.
Market Cap (USD): $440.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

161. Gemini Therapeutics, Inc.

Company Profile: Gemini Therapeutics, Inc.
Market Cap (USD): $438.8 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

162. PureTech Health plc

Company Profile: PureTech Health plc
Market Cap (USD): $432.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

163. Concert Pharmaceuticals, Inc.

Company Profile: Concert Pharmaceuticals, Inc.
Market Cap (USD): $401.9 M (June 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

164. CytomX Therapeutics, Inc.

Company Profile: CytomX Therapeutics, Inc.
Market Cap (USD): $393.9 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

165. iTeos Therapeutics, Inc.

Company Profile: iTeos Therapeutics, Inc.
Market Cap (USD): $389.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

166. Eton Pharmaceuticals, Inc.

Company Profile: Eton Pharmaceuticals, Inc.
Market Cap (USD): $387.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

167. Altimmune, Inc.

Company Profile: Altimmune, Inc.
Market Cap (USD): $386.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

168. Compass Therapeutics, Inc.

Company Profile: Compass Therapeutics, Inc.
Market Cap (USD): $384.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

169. Revance Therapeutics, Inc.

Company Profile: Revance Therapeutics, Inc.
Market Cap (USD): $381.0 M (Jan. 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

170. Savara Inc.

Company Profile: Savara Inc.
Market Cap (USD): $378.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

171. Terns Pharmaceuticals, Inc.

Company Profile: Terns Pharmaceuticals, Inc.
Market Cap (USD): $377.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

172. Arcturus Therapeutics Holdings Inc.

Company Profile: Arcturus Therapeutics Holdings Inc.
Market Cap (USD): $373.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

173. Fulcrum Therapeutics, Inc.

Company Profile: Fulcrum Therapeutics, Inc.
Market Cap (USD): $373.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

174. Aquestive Therapeutics, Inc.

Company Profile: Aquestive Therapeutics, Inc.
Market Cap (USD): $369.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

175. Northwest Biotherapeutics, Inc.

Company Profile: Northwest Biotherapeutics, Inc.
Market Cap (USD): $359.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

176. Chimerix, Inc.

Company Profile: Chimerix, Inc.
Market Cap (USD): $356.3 M (Jan. 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

177. CytoDyn, Inc.

Company Profile: CytoDyn, Inc.
Market Cap (USD): $351.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

178. Silverback Therapeutics, Inc.

Company Profile: Silverback Therapeutics, Inc.
Market Cap (USD): $341.8 M (July 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

179. Rigel Pharmaceuticals, Inc.

Company Profile: Rigel Pharmaceuticals, Inc.
Market Cap (USD): $338.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

180. Heron Therapeutics, Inc.

Company Profile: Heron Therapeutics, Inc.
Market Cap (USD): $335.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

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