United States

Top 538 largest US Companies in the Biotechnology industry by Market Cap

This is the list of the largest public listed companies in the Biotechnology industry from the United States by market capitalization with links to their reference stock.

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Top Biotechnology Companies from the United States as of Jul. 01, 2025

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Rank Company Market Cap (USD) Country Sector Industry
211 Codexis, Inc. $229.5 M United States US Healthcare US Biotechnology
212 Editas Medicine, Inc. $215.1 M United States US Healthcare US Biotechnology
213 Design Therapeutics, Inc. $214.0 M United States US Healthcare US Biotechnology
214 scPharmaceuticals Inc. $209.6 M United States US Healthcare US Biotechnology
215 Kodiak Sciences Inc. $208.4 M United States US Healthcare US Biotechnology
216 Zevra Therapeutics, Inc. $205.3 M

(Jan. 1, 2023)

 United States US Healthcare US Biotechnology
217 Larimar Therapeutics, Inc. $204.9 M United States US Healthcare US Biotechnology
218 BioStem Technologies, Inc. $199.3 M United States US Healthcare US Biotechnology
219 4D Molecular Therapeutics, Inc. $196.4 M United States US Healthcare US Biotechnology
220 LogicBio Therapeutics, Inc. $194.8 M United States US Healthcare US Biotechnology
221 Y-mAbs Therapeutics, Inc. $194.8 M United States US Healthcare US Biotechnology
222 Spectrum Pharmaceuticals, Inc. $192.9 M

(July 1, 2023)

 United States US Healthcare US Biotechnology
223 Merrimack Pharmaceuticals, Inc. $189.8 M

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology
224 Omeros Corporation $187.5 M United States US Healthcare US Biotechnology
225 ZIOPHARM Oncology, Inc. $187.1 M

(June 1, 2022)

 United States US Healthcare US Biotechnology
226 Eledon Pharmaceuticals, Inc. $184.4 M United States US Healthcare US Biotechnology
227 Instil Bio, Inc. $180.4 M United States US Healthcare US Biotechnology
228 Harpoon Therapeutics, Inc. $178.6 M

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology
229 Puma Biotechnology, Inc. $177.7 M United States US Healthcare US Biotechnology
230 Voyager Therapeutics, Inc. $177.1 M United States US Healthcare US Biotechnology
231 Berkeley Lights, Inc. $168.7 M

(Jan. 1, 2023)

 United States US Healthcare US Biotechnology
232 Enanta Pharmaceuticals, Inc. $168.7 M United States US Healthcare US Biotechnology
233 Agenus Inc. $166.4 M United States US Healthcare US Biotechnology
234 Mind Medicine MindMed, Inc. $164.0 M

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology
235 Spero Therapeutics, Inc. $162.7 M United States US Healthcare US Biotechnology
236 Anika Therapeutics, Inc. $161.3 M United States US Healthcare US Biotechnology
237 DiaMedica Therapeutics Inc. $161.2 M United States US Healthcare US Biotechnology
238 Aclaris Therapeutics, Inc. $155.9 M United States US Healthcare US Biotechnology
239 La Jolla Pharmaceutical Company $155.1 M

(Aug. 1, 2022)

 United States US Healthcare US Biotechnology
240 Alector, Inc. $151.0 M United States US Healthcare US Biotechnology

Top Biotechnology Companies from the United States as of Jul. 01, 2025

211. Codexis, Inc.

Company Profile: Codexis, Inc.
Market Cap (USD): $229.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

212. Editas Medicine, Inc.

Company Profile: Editas Medicine, Inc.
Market Cap (USD): $215.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

213. Design Therapeutics, Inc.

Company Profile: Design Therapeutics, Inc.
Market Cap (USD): $214.0 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

214. scPharmaceuticals Inc.

Company Profile: scPharmaceuticals Inc.
Market Cap (USD): $209.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

215. Kodiak Sciences Inc.

Company Profile: Kodiak Sciences Inc.
Market Cap (USD): $208.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

216. Zevra Therapeutics, Inc.

Company Profile: Zevra Therapeutics, Inc.
Market Cap (USD): $205.3 M (Jan. 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

217. Larimar Therapeutics, Inc.

Company Profile: Larimar Therapeutics, Inc.
Market Cap (USD): $204.9 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

218. BioStem Technologies, Inc.

Company Profile: BioStem Technologies, Inc.
Market Cap (USD): $199.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

219. 4D Molecular Therapeutics, Inc.

Company Profile: 4D Molecular Therapeutics, Inc.
Market Cap (USD): $196.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

220. LogicBio Therapeutics, Inc.

Company Profile: LogicBio Therapeutics, Inc.
Market Cap (USD): $194.8 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

221. Y-mAbs Therapeutics, Inc.

Company Profile: Y-mAbs Therapeutics, Inc.
Market Cap (USD): $194.8 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

222. Spectrum Pharmaceuticals, Inc.

Company Profile: Spectrum Pharmaceuticals, Inc.
Market Cap (USD): $192.9 M (July 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

223. Merrimack Pharmaceuticals, Inc.

Company Profile: Merrimack Pharmaceuticals, Inc.
Market Cap (USD): $189.8 M (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

224. Omeros Corporation

Company Profile: Omeros Corporation
Market Cap (USD): $187.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

225. ZIOPHARM Oncology, Inc.

Company Profile: ZIOPHARM Oncology, Inc.
Market Cap (USD): $187.1 M (June 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

226. Eledon Pharmaceuticals, Inc.

Company Profile: Eledon Pharmaceuticals, Inc.
Market Cap (USD): $184.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

227. Instil Bio, Inc.

Company Profile: Instil Bio, Inc.
Market Cap (USD): $180.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

228. Harpoon Therapeutics, Inc.

Company Profile: Harpoon Therapeutics, Inc.
Market Cap (USD): $178.6 M (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

229. Puma Biotechnology, Inc.

Company Profile: Puma Biotechnology, Inc.
Market Cap (USD): $177.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

230. Voyager Therapeutics, Inc.

Company Profile: Voyager Therapeutics, Inc.
Market Cap (USD): $177.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

231. Berkeley Lights, Inc.

Company Profile: Berkeley Lights, Inc.
Market Cap (USD): $168.7 M (Jan. 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

232. Enanta Pharmaceuticals, Inc.

Company Profile: Enanta Pharmaceuticals, Inc.
Market Cap (USD): $168.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

233. Agenus Inc.

Company Profile: Agenus Inc.
Market Cap (USD): $166.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

234. Mind Medicine MindMed, Inc.

Company Profile: Mind Medicine MindMed, Inc.
Market Cap (USD): $164.0 M (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

235. Spero Therapeutics, Inc.

Company Profile: Spero Therapeutics, Inc.
Market Cap (USD): $162.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

236. Anika Therapeutics, Inc.

Company Profile: Anika Therapeutics, Inc.
Market Cap (USD): $161.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

237. DiaMedica Therapeutics Inc.

Company Profile: DiaMedica Therapeutics Inc.
Market Cap (USD): $161.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

238. Aclaris Therapeutics, Inc.

Company Profile: Aclaris Therapeutics, Inc.
Market Cap (USD): $155.9 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

239. La Jolla Pharmaceutical Company

Company Profile: La Jolla Pharmaceutical Company
Market Cap (USD): $155.1 M (Aug. 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

240. Alector, Inc.

Company Profile: Alector, Inc.
Market Cap (USD): $151.0 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

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