United States

Top 538 largest US Companies in the Biotechnology industry by Market Cap

This is the list of the largest public listed companies in the Biotechnology industry from the United States by market capitalization with links to their reference stock.

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Top Biotechnology Companies from the United States as of Jul. 01, 2025

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Rank Company Market Cap (USD) Country Sector Industry
271 C4 Therapeutics, Inc. $105.1 M United States US Healthcare US Biotechnology
272 Entasis Therapeutics Holdings Inc. $104.8 M

(June 1, 2024)

 United States US Healthcare US Biotechnology
273 Seres Therapeutics, Inc. $103.7 M United States US Healthcare US Biotechnology
274 Nautilus Biotechnology, Inc. $103.4 M United States US Healthcare US Biotechnology
275 Jounce Therapeutics, Inc. $101.6 M

(May 1, 2023)

 United States US Healthcare US Biotechnology
276 Vaxart, Inc. $97.5 M United States US Healthcare US Biotechnology
277 Cassava Sciences, Inc. $97.1 M United States US Healthcare US Biotechnology
278 XBiotech Inc. $97.0 M United States US Healthcare US Biotechnology
279 Biomea Fusion, Inc. $94.7 M United States US Healthcare US Biotechnology
280 Coherus BioSciences, Inc. $93.9 M United States US Healthcare US Biotechnology
281 Osmotica Pharmaceuticals plc $92.5 M

(June 1, 2022)

 United States US Healthcare US Biotechnology
282 MacroGenics, Inc. $92.1 M United States US Healthcare US Biotechnology
283 Zentalis Pharmaceuticals, Inc. $90.7 M United States US Healthcare US Biotechnology
284 BeyondSpring Inc. $89.9 M United States US Healthcare US Biotechnology
285 Oramed Pharmaceuticals Inc. $89.1 M United States US Healthcare US Biotechnology
286 Veru Inc. $88.9 M United States US Healthcare US Biotechnology
287 IGM Biosciences, Inc. $81.9 M United States US Healthcare US Biotechnology
288 Eyenovia, Inc. $80.8 M United States US Healthcare US Biotechnology
289 Decibel Therapeutics, Inc. $80.3 M

(July 1, 2023)

 United States US Healthcare US Biotechnology
290 Armata Pharmaceuticals Inc. $78.5 M United States US Healthcare US Biotechnology
291 Pliant Therapeutics, Inc. $77.3 M United States US Healthcare US Biotechnology
292 bluebird bio, Inc. $76.5 M

(Jan. 1, 2025)

 United States US Healthcare US Biotechnology
293 Outlook Therapeutics, Inc. $76.3 M United States US Healthcare US Biotechnology
294 Biostage, Inc. $75.9 M

(Jan. 1, 2023)

 United States US Healthcare US Biotechnology
295 Immunic, Inc. $69.7 M United States US Healthcare US Biotechnology
296 Anebulo Pharmaceuticals, Inc. $69.0 M United States US Healthcare US Biotechnology
297 Biotech Products Services and Research, Inc. $66.1 M

(Nov. 1, 2021)

 United States US Healthcare US Biotechnology
298 Aerpio Pharmaceuticals, Inc. $66.0 M

(July 1, 2024)

 United States US Healthcare US Biotechnology
299 Verrica Pharmaceuticals Inc. $65.4 M United States US Healthcare US Biotechnology
300 Sutro Biopharma, Inc. $64.5 M United States US Healthcare US Biotechnology

Top Biotechnology Companies from the United States as of Jul. 01, 2025

271. C4 Therapeutics, Inc.

Company Profile: C4 Therapeutics, Inc.
Market Cap (USD): $105.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

272. Entasis Therapeutics Holdings Inc.

Company Profile: Entasis Therapeutics Holdings Inc.
Market Cap (USD): $104.8 M (June 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

273. Seres Therapeutics, Inc.

Company Profile: Seres Therapeutics, Inc.
Market Cap (USD): $103.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

274. Nautilus Biotechnology, Inc.

Company Profile: Nautilus Biotechnology, Inc.
Market Cap (USD): $103.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

275. Jounce Therapeutics, Inc.

Company Profile: Jounce Therapeutics, Inc.
Market Cap (USD): $101.6 M (May 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

276. Vaxart, Inc.

Company Profile: Vaxart, Inc.
Market Cap (USD): $97.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

277. Cassava Sciences, Inc.

Company Profile: Cassava Sciences, Inc.
Market Cap (USD): $97.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

278. XBiotech Inc.

Company Profile: XBiotech Inc.
Market Cap (USD): $97.0 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

279. Biomea Fusion, Inc.

Company Profile: Biomea Fusion, Inc.
Market Cap (USD): $94.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

280. Coherus BioSciences, Inc.

Company Profile: Coherus BioSciences, Inc.
Market Cap (USD): $93.9 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

281. Osmotica Pharmaceuticals plc

Company Profile: Osmotica Pharmaceuticals plc
Market Cap (USD): $92.5 M (June 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

282. MacroGenics, Inc.

Company Profile: MacroGenics, Inc.
Market Cap (USD): $92.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

283. Zentalis Pharmaceuticals, Inc.

Company Profile: Zentalis Pharmaceuticals, Inc.
Market Cap (USD): $90.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

284. BeyondSpring Inc.

Company Profile: BeyondSpring Inc.
Market Cap (USD): $89.9 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

285. Oramed Pharmaceuticals Inc.

Company Profile: Oramed Pharmaceuticals Inc.
Market Cap (USD): $89.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

286. Veru Inc.

Company Profile: Veru Inc.
Market Cap (USD): $88.9 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

287. IGM Biosciences, Inc.

Company Profile: IGM Biosciences, Inc.
Market Cap (USD): $81.9 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

288. Eyenovia, Inc.

Company Profile: Eyenovia, Inc.
Market Cap (USD): $80.8 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

289. Decibel Therapeutics, Inc.

Company Profile: Decibel Therapeutics, Inc.
Market Cap (USD): $80.3 M (July 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

290. Armata Pharmaceuticals Inc.

Company Profile: Armata Pharmaceuticals Inc.
Market Cap (USD): $78.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

291. Pliant Therapeutics, Inc.

Company Profile: Pliant Therapeutics, Inc.
Market Cap (USD): $77.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

292. bluebird bio, Inc.

Company Profile: bluebird bio, Inc.
Market Cap (USD): $76.5 M (Jan. 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

293. Outlook Therapeutics, Inc.

Company Profile: Outlook Therapeutics, Inc.
Market Cap (USD): $76.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

294. Biostage, Inc.

Company Profile: Biostage, Inc.
Market Cap (USD): $75.9 M (Jan. 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

295. Immunic, Inc.

Company Profile: Immunic, Inc.
Market Cap (USD): $69.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

296. Anebulo Pharmaceuticals, Inc.

Company Profile: Anebulo Pharmaceuticals, Inc.
Market Cap (USD): $69.0 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

297. Biotech Products Services and Research, Inc.

Company Profile: Biotech Products Services and Research, Inc.
Market Cap (USD): $66.1 M (Nov. 1, 2021)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

298. Aerpio Pharmaceuticals, Inc.

Company Profile: Aerpio Pharmaceuticals, Inc.
Market Cap (USD): $66.0 M (July 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

299. Verrica Pharmaceuticals Inc.

Company Profile: Verrica Pharmaceuticals Inc.
Market Cap (USD): $65.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

300. Sutro Biopharma, Inc.

Company Profile: Sutro Biopharma, Inc.
Market Cap (USD): $64.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

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