United States

Top 538 largest US Companies in the Biotechnology industry by Market Cap

This is the list of the largest public listed companies in the Biotechnology industry from the United States by market capitalization with links to their reference stock.

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Top Biotechnology Companies from the United States as of Jan. 01, 2026

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Rank Company Market Cap (USD) Country Sector Industry
391 Lyra Therapeutics, Inc. $5.6 M United States US Healthcare US Biotechnology
392 AVROBIO, Inc. $5.2 M

(July 1, 2024)

 United States US Healthcare US Biotechnology
393 Cyclerion Therapeutics, Inc. $5.1 M United States US Healthcare US Biotechnology
394 180 Life Sciences Corp. $5.0 M

(July 1, 2025)

 United States US Healthcare US Biotechnology
395 Xenetic Biosciences, Inc. $4.9 M United States US Healthcare US Biotechnology
396 NanoString Technologies, Inc. $3.4 M

(May 1, 2025)

 United States US Healthcare US Biotechnology
397 Vallon Pharmaceuticals, Inc. $3.3 M United States US Healthcare US Biotechnology
398 Oncorus, Inc. $3.3 M

(Dec. 1, 2023)

 United States US Healthcare US Biotechnology
399 Virios Therapeutics, LLC $3.2 M United States US Healthcare US Biotechnology
400 CNS Pharmaceuticals, Inc. $3.0 M United States US Healthcare US Biotechnology
401 Vaccinex, Inc. $3.0 M United States US Healthcare US Biotechnology
402 Artelo Biosciences, Inc. $2.6 M United States US Healthcare US Biotechnology
403 InVivo Therapeutics Holdings Corp. $2.4 M

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology
404 Avenue Therapeutics, Inc. $2.2 M United States US Healthcare US Biotechnology
405 Sorrento Therapeutics, Inc. $1.7 M United States US Healthcare US Biotechnology
406 Galera Therapeutics, Inc. $1.7 M United States US Healthcare US Biotechnology
407 ADiTx Therapeutics, Inc. $1.6 M United States US Healthcare US Biotechnology
408 Enzolytics, Inc. $1.4 M United States US Healthcare US Biotechnology
409 Baudax Bio, Inc. $1.4 M

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology
410 Vyant Bio, Inc. $1.2 M

(Dec. 1, 2023)

 United States US Healthcare US Biotechnology
411 CohBar, Inc. $1.2 M

(Jan. 1, 2025)

 United States US Healthcare US Biotechnology
412 Axcella Health Inc. $1.2 M

(Dec. 1, 2023)

 United States US Healthcare US Biotechnology
413 Orgenesis Inc. $775,695 United States US Healthcare US Biotechnology
414 Petros Pharmaceuticals, Inc. $313,553 United States US Healthcare US Biotechnology
415 Kiromic BioPharma, Inc. $214,931

(July 1, 2025)

 United States US Healthcare US Biotechnology
416 Translate Bio, Inc. $88,790 United States US Healthcare US Biotechnology
417 Vincera Pharma, Inc. $68,045 United States US Healthcare US Biotechnology
418 Panbela Therapeutics Inc. $24,759 United States US Healthcare US Biotechnology
419 Scopus BioPharma Inc. $16,833 United States US Healthcare US Biotechnology
420 Virpax Pharmaceuticals, Inc. $13,667 United States US Healthcare US Biotechnology

Top Biotechnology Companies from the United States as of Jan. 01, 2026

391. Lyra Therapeutics, Inc.

Company Profile: Lyra Therapeutics, Inc.
Market Cap (USD): $5.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

392. AVROBIO, Inc.

Company Profile: AVROBIO, Inc.
Market Cap (USD): $5.2 M (July 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

393. Cyclerion Therapeutics, Inc.

Company Profile: Cyclerion Therapeutics, Inc.
Market Cap (USD): $5.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

394. 180 Life Sciences Corp.

Company Profile: 180 Life Sciences Corp.
Market Cap (USD): $5.0 M (July 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

395. Xenetic Biosciences, Inc.

Company Profile: Xenetic Biosciences, Inc.
Market Cap (USD): $4.9 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

396. NanoString Technologies, Inc.

Company Profile: NanoString Technologies, Inc.
Market Cap (USD): $3.4 M (May 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

397. Vallon Pharmaceuticals, Inc.

Company Profile: Vallon Pharmaceuticals, Inc.
Market Cap (USD): $3.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

398. Oncorus, Inc.

Company Profile: Oncorus, Inc.
Market Cap (USD): $3.3 M (Dec. 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

399. Virios Therapeutics, LLC

Company Profile: Virios Therapeutics, LLC
Market Cap (USD): $3.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

400. CNS Pharmaceuticals, Inc.

Company Profile: CNS Pharmaceuticals, Inc.
Market Cap (USD): $3.0 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

401. Vaccinex, Inc.

Company Profile: Vaccinex, Inc.
Market Cap (USD): $3.0 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

402. Artelo Biosciences, Inc.

Company Profile: Artelo Biosciences, Inc.
Market Cap (USD): $2.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

403. InVivo Therapeutics Holdings Corp.

Company Profile: InVivo Therapeutics Holdings Corp.
Market Cap (USD): $2.4 M (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

404. Avenue Therapeutics, Inc.

Company Profile: Avenue Therapeutics, Inc.
Market Cap (USD): $2.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

405. Sorrento Therapeutics, Inc.

Company Profile: Sorrento Therapeutics, Inc.
Market Cap (USD): $1.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

406. Galera Therapeutics, Inc.

Company Profile: Galera Therapeutics, Inc.
Market Cap (USD): $1.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

407. ADiTx Therapeutics, Inc.

Company Profile: ADiTx Therapeutics, Inc.
Market Cap (USD): $1.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

408. Enzolytics, Inc.

Company Profile: Enzolytics, Inc.
Market Cap (USD): $1.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

409. Baudax Bio, Inc.

Company Profile: Baudax Bio, Inc.
Market Cap (USD): $1.4 M (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

410. Vyant Bio, Inc.

Company Profile: Vyant Bio, Inc.
Market Cap (USD): $1.2 M (Dec. 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

411. CohBar, Inc.

Company Profile: CohBar, Inc.
Market Cap (USD): $1.2 M (Jan. 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

412. Axcella Health Inc.

Company Profile: Axcella Health Inc.
Market Cap (USD): $1.2 M (Dec. 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

413. Orgenesis Inc.

Company Profile: Orgenesis Inc.
Market Cap (USD): $775,695
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

414. Petros Pharmaceuticals, Inc.

Company Profile: Petros Pharmaceuticals, Inc.
Market Cap (USD): $313,553
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

415. Kiromic BioPharma, Inc.

Company Profile: Kiromic BioPharma, Inc.
Market Cap (USD): $214,931 (July 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

416. Translate Bio, Inc.

Company Profile: Translate Bio, Inc.
Market Cap (USD): $88,790
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

417. Vincera Pharma, Inc.

Company Profile: Vincera Pharma, Inc.
Market Cap (USD): $68,045
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

418. Panbela Therapeutics Inc.

Company Profile: Panbela Therapeutics Inc.
Market Cap (USD): $24,759
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

419. Scopus BioPharma Inc.

Company Profile: Scopus BioPharma Inc.
Market Cap (USD): $16,833
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

420. Virpax Pharmaceuticals, Inc.

Company Profile: Virpax Pharmaceuticals, Inc.
Market Cap (USD): $13,667
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

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