United States

Top 538 largest US Companies in the Biotechnology industry by Market Cap

This is the list of the largest public listed companies in the Biotechnology industry from the United States by market capitalization with links to their reference stock.

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Top Biotechnology Companies from the United States as of Jan. 01, 2026

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Rank Company Market Cap (USD) Country Sector Industry
331 Reneo Pharmaceuticals, Inc. $50.7 M

(July 1, 2024)

 United States US Healthcare US Biotechnology
332 Gain Therapeutics, Inc. $50.6 M

(July 1, 2025)

 United States US Healthcare US Biotechnology
333 Adicet Bio, Inc. $50.2 M

(July 1, 2025)

 United States US Healthcare US Biotechnology
334 AlloVir, Inc. $49.5 M

(July 1, 2025)

 United States US Healthcare US Biotechnology
335 Aeglea BioTherapeutics, Inc. $48.6 M

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology
336 Vicapsys Life Sciences, Inc. $48.6 M United States US Healthcare US Biotechnology
337 Werewolf Therapeutics, Inc. $48.0 M

(July 1, 2025)

 United States US Healthcare US Biotechnology
338 Aligos Therapeutics, Inc. $47.9 M

(July 1, 2025)

 United States US Healthcare US Biotechnology
339 Synaptogenix, Inc. $47.9 M United States US Healthcare US Biotechnology
340 Kezar Life Sciences, Inc. $46.1 M United States US Healthcare US Biotechnology
341 Aileron Therapeutics, Inc. $45.7 M

(March 1, 2025)

 United States US Healthcare US Biotechnology
342 PDS Biotechnology Corporation $45.6 M United States US Healthcare US Biotechnology
343 Actinium Pharmaceuticals, Inc. $42.7 M United States US Healthcare US Biotechnology
344 CEL-SCI Corporation $41.3 M United States US Healthcare US Biotechnology
345 Rain Therapeutics, Inc. $40.9 M United States US Healthcare US Biotechnology
346 INmune Bio, Inc. $40.9 M United States US Healthcare US Biotechnology
347 BioXcel Therapeutics, Inc. $37.2 M United States US Healthcare US Biotechnology
348 Passage Bio, Inc. $37.2 M United States US Healthcare US Biotechnology
349 FibroGen, Inc. $37.1 M United States US Healthcare US Biotechnology
350 Generation Bio Co. $36.7 M United States US Healthcare US Biotechnology
351 Reviva Pharmaceuticals Holdings, Inc. $36.2 M United States US Healthcare US Biotechnology
352 Lantern Pharma Inc. $34.8 M United States US Healthcare US Biotechnology
353 Zivo Bioscience, Inc. $34.0 M United States US Healthcare US Biotechnology
354 Dyadic International, Inc. $34.0 M United States US Healthcare US Biotechnology
355 BioAtla, Inc. $31.4 M United States US Healthcare US Biotechnology
356 Angion Biomedica Corp $30.1 M

(June 1, 2023)

 United States US Healthcare US Biotechnology
357 Marinus Pharmaceuticals, Inc. $29.9 M

(Jan. 1, 2025)

 United States US Healthcare US Biotechnology
358 Aytu BioScience, Inc. $28.2 M United States US Healthcare US Biotechnology
359 Athira Pharma, Inc. $27.4 M United States US Healthcare US Biotechnology
360 Cyclo Therapeutics, Inc. $26.9 M

(Jan. 1, 2025)

 United States US Healthcare US Biotechnology

Top Biotechnology Companies from the United States as of Jan. 01, 2026

331. Reneo Pharmaceuticals, Inc.

Company Profile: Reneo Pharmaceuticals, Inc.
Market Cap (USD): $50.7 M (July 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

332. Gain Therapeutics, Inc.

Company Profile: Gain Therapeutics, Inc.
Market Cap (USD): $50.6 M (July 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

333. Adicet Bio, Inc.

Company Profile: Adicet Bio, Inc.
Market Cap (USD): $50.2 M (July 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

334. AlloVir, Inc.

Company Profile: AlloVir, Inc.
Market Cap (USD): $49.5 M (July 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

335. Aeglea BioTherapeutics, Inc.

Company Profile: Aeglea BioTherapeutics, Inc.
Market Cap (USD): $48.6 M (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

336. Vicapsys Life Sciences, Inc.

Company Profile: Vicapsys Life Sciences, Inc.
Market Cap (USD): $48.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

337. Werewolf Therapeutics, Inc.

Company Profile: Werewolf Therapeutics, Inc.
Market Cap (USD): $48.0 M (July 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

338. Aligos Therapeutics, Inc.

Company Profile: Aligos Therapeutics, Inc.
Market Cap (USD): $47.9 M (July 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

339. Synaptogenix, Inc.

Company Profile: Synaptogenix, Inc.
Market Cap (USD): $47.9 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

340. Kezar Life Sciences, Inc.

Company Profile: Kezar Life Sciences, Inc.
Market Cap (USD): $46.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

341. Aileron Therapeutics, Inc.

Company Profile: Aileron Therapeutics, Inc.
Market Cap (USD): $45.7 M (March 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

342. PDS Biotechnology Corporation

Company Profile: PDS Biotechnology Corporation
Market Cap (USD): $45.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

343. Actinium Pharmaceuticals, Inc.

Company Profile: Actinium Pharmaceuticals, Inc.
Market Cap (USD): $42.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

344. CEL-SCI Corporation

Company Profile: CEL-SCI Corporation
Market Cap (USD): $41.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

345. Rain Therapeutics, Inc.

Company Profile: Rain Therapeutics, Inc.
Market Cap (USD): $40.9 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

346. INmune Bio, Inc.

Company Profile: INmune Bio, Inc.
Market Cap (USD): $40.9 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

347. BioXcel Therapeutics, Inc.

Company Profile: BioXcel Therapeutics, Inc.
Market Cap (USD): $37.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

348. Passage Bio, Inc.

Company Profile: Passage Bio, Inc.
Market Cap (USD): $37.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

349. FibroGen, Inc.

Company Profile: FibroGen, Inc.
Market Cap (USD): $37.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

350. Generation Bio Co.

Company Profile: Generation Bio Co.
Market Cap (USD): $36.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

351. Reviva Pharmaceuticals Holdings, Inc.

Company Profile: Reviva Pharmaceuticals Holdings, Inc.
Market Cap (USD): $36.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

352. Lantern Pharma Inc.

Company Profile: Lantern Pharma Inc.
Market Cap (USD): $34.8 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

353. Zivo Bioscience, Inc.

Company Profile: Zivo Bioscience, Inc.
Market Cap (USD): $34.0 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

354. Dyadic International, Inc.

Company Profile: Dyadic International, Inc.
Market Cap (USD): $34.0 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

355. BioAtla, Inc.

Company Profile: BioAtla, Inc.
Market Cap (USD): $31.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

356. Angion Biomedica Corp

Company Profile: Angion Biomedica Corp
Market Cap (USD): $30.1 M (June 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

357. Marinus Pharmaceuticals, Inc.

Company Profile: Marinus Pharmaceuticals, Inc.
Market Cap (USD): $29.9 M (Jan. 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

358. Aytu BioScience, Inc.

Company Profile: Aytu BioScience, Inc.
Market Cap (USD): $28.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

359. Athira Pharma, Inc.

Company Profile: Athira Pharma, Inc.
Market Cap (USD): $27.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

360. Cyclo Therapeutics, Inc.

Company Profile: Cyclo Therapeutics, Inc.
Market Cap (USD): $26.9 M (Jan. 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

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