United States

Top 538 largest US Companies in the Biotechnology industry by Market Cap

This is the list of the largest public listed companies in the Biotechnology industry from the United States by market capitalization with links to their reference stock.

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Top Biotechnology Companies from the United States as of Jul. 01, 2025

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Rank Company Market Cap (USD) Country Sector Industry
241 Black Diamond Therapeutics, Inc. $146.7 M United States US Healthcare US Biotechnology
242 Cabaletta Bio, Inc. $146.6 M United States US Healthcare US Biotechnology
243 Checkpoint Therapeutics, Inc. $146.5 M

(Jan. 1, 2025)

 United States US Healthcare US Biotechnology
244 Lyell Immunopharma, Inc. $143.5 M United States US Healthcare US Biotechnology
245 Inhibikase Therapeutics, Inc. $140.5 M United States US Healthcare US Biotechnology
246 Assembly Biosciences, Inc. $138.5 M United States US Healthcare US Biotechnology
247 Galectin Therapeutics, Inc. $138.0 M United States US Healthcare US Biotechnology
248 Talaris Therapeutics, Inc. $137.4 M

(July 1, 2023)

 United States US Healthcare US Biotechnology
249 Strongbridge Biopharma plc $135.7 M

(Oct. 1, 2021)

 United States US Healthcare US Biotechnology
250 Selecta Biosciences, Inc. $135.2 M

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology
251 Greenwich LifeSciences, Inc. $134.1 M United States US Healthcare US Biotechnology
252 Seer, Inc. $133.6 M United States US Healthcare US Biotechnology
253 RAPT Therapeutics, Inc. $133.1 M United States US Healthcare US Biotechnology
254 G1 Therapeutics, Inc. $131.2 M

(July 1, 2024)

 United States US Healthcare US Biotechnology
255 aTyr Pharma, Inc. $131.1 M United States US Healthcare US Biotechnology
256 Sangamo Therapeutics, Inc. $129.3 M United States US Healthcare US Biotechnology
257 Fate Therapeutics, Inc. $128.4 M United States US Healthcare US Biotechnology
258 Sesen Bio, Inc. $128.0 M

(March 1, 2023)

 United States US Healthcare US Biotechnology
259 Paratek Pharmaceuticals, Inc. $125.7 M

(July 1, 2023)

 United States US Healthcare US Biotechnology
260 Nkarta, Inc. $124.2 M United States US Healthcare US Biotechnology
261 Graybug Vision, Inc. $121.0 M

(May 1, 2023)

 United States US Healthcare US Biotechnology
262 Progenity, Inc. $120.7 M

(July 1, 2024)

 United States US Healthcare US Biotechnology
263 Kinnate Biopharma Inc. $113.5 M

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology
264 NGM Biopharmaceuticals, Inc. $110.8 M

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology
265 Atossa Therapeutics, Inc. $109.7 M United States US Healthcare US Biotechnology
266 Catabasis Pharmaceuticals, Inc. $109.5 M

(June 1, 2022)

 United States US Healthcare US Biotechnology
267 Cyteir Therapeutics, Inc. $109.1 M

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology
268 Allakos Inc. $108.1 M

(Jan. 1, 2025)

 United States US Healthcare US Biotechnology
269 Opiant Pharmaceuticals, Inc. $107.5 M

(Jan. 1, 2023)

 United States US Healthcare US Biotechnology
270 Champions Oncology, Inc. $106.2 M United States US Healthcare US Biotechnology

Top Biotechnology Companies from the United States as of Jul. 01, 2025

241. Black Diamond Therapeutics, Inc.

Company Profile: Black Diamond Therapeutics, Inc.
Market Cap (USD): $146.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

242. Cabaletta Bio, Inc.

Company Profile: Cabaletta Bio, Inc.
Market Cap (USD): $146.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

243. Checkpoint Therapeutics, Inc.

Company Profile: Checkpoint Therapeutics, Inc.
Market Cap (USD): $146.5 M (Jan. 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

244. Lyell Immunopharma, Inc.

Company Profile: Lyell Immunopharma, Inc.
Market Cap (USD): $143.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

245. Inhibikase Therapeutics, Inc.

Company Profile: Inhibikase Therapeutics, Inc.
Market Cap (USD): $140.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

246. Assembly Biosciences, Inc.

Company Profile: Assembly Biosciences, Inc.
Market Cap (USD): $138.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

247. Galectin Therapeutics, Inc.

Company Profile: Galectin Therapeutics, Inc.
Market Cap (USD): $138.0 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

248. Talaris Therapeutics, Inc.

Company Profile: Talaris Therapeutics, Inc.
Market Cap (USD): $137.4 M (July 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

249. Strongbridge Biopharma plc

Company Profile: Strongbridge Biopharma plc
Market Cap (USD): $135.7 M (Oct. 1, 2021)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

250. Selecta Biosciences, Inc.

Company Profile: Selecta Biosciences, Inc.
Market Cap (USD): $135.2 M (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

251. Greenwich LifeSciences, Inc.

Company Profile: Greenwich LifeSciences, Inc.
Market Cap (USD): $134.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

252. Seer, Inc.

Company Profile: Seer, Inc.
Market Cap (USD): $133.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

253. RAPT Therapeutics, Inc.

Company Profile: RAPT Therapeutics, Inc.
Market Cap (USD): $133.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

254. G1 Therapeutics, Inc.

Company Profile: G1 Therapeutics, Inc.
Market Cap (USD): $131.2 M (July 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

255. aTyr Pharma, Inc.

Company Profile: aTyr Pharma, Inc.
Market Cap (USD): $131.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

256. Sangamo Therapeutics, Inc.

Company Profile: Sangamo Therapeutics, Inc.
Market Cap (USD): $129.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

257. Fate Therapeutics, Inc.

Company Profile: Fate Therapeutics, Inc.
Market Cap (USD): $128.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

258. Sesen Bio, Inc.

Company Profile: Sesen Bio, Inc.
Market Cap (USD): $128.0 M (March 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

259. Paratek Pharmaceuticals, Inc.

Company Profile: Paratek Pharmaceuticals, Inc.
Market Cap (USD): $125.7 M (July 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

260. Nkarta, Inc.

Company Profile: Nkarta, Inc.
Market Cap (USD): $124.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

261. Graybug Vision, Inc.

Company Profile: Graybug Vision, Inc.
Market Cap (USD): $121.0 M (May 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

262. Progenity, Inc.

Company Profile: Progenity, Inc.
Market Cap (USD): $120.7 M (July 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

263. Kinnate Biopharma Inc.

Company Profile: Kinnate Biopharma Inc.
Market Cap (USD): $113.5 M (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

264. NGM Biopharmaceuticals, Inc.

Company Profile: NGM Biopharmaceuticals, Inc.
Market Cap (USD): $110.8 M (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

265. Atossa Therapeutics, Inc.

Company Profile: Atossa Therapeutics, Inc.
Market Cap (USD): $109.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

266. Catabasis Pharmaceuticals, Inc.

Company Profile: Catabasis Pharmaceuticals, Inc.
Market Cap (USD): $109.5 M (June 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

267. Cyteir Therapeutics, Inc.

Company Profile: Cyteir Therapeutics, Inc.
Market Cap (USD): $109.1 M (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

268. Allakos Inc.

Company Profile: Allakos Inc.
Market Cap (USD): $108.1 M (Jan. 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

269. Opiant Pharmaceuticals, Inc.

Company Profile: Opiant Pharmaceuticals, Inc.
Market Cap (USD): $107.5 M (Jan. 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

270. Champions Oncology, Inc.

Company Profile: Champions Oncology, Inc.
Market Cap (USD): $106.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

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