United States

Top 538 largest US Companies in the Biotechnology industry by Market Cap

This is the list of the largest public listed companies in the Biotechnology industry from the United States by market capitalization with links to their reference stock.

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Top Biotechnology Companies from the United States as of Jan. 01, 2026

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Rank Company Market Cap (USD) Country Sector Industry
241 Cardiff Oncology, Inc. $179.2 M United States US Healthcare US Biotechnology
242 Harpoon Therapeutics, Inc. $178.6 M

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology
243 Arcturus Therapeutics Holdings Inc. $177.6 M United States US Healthcare US Biotechnology
244 Prelude Therapeutics Incorporated $171.6 M United States US Healthcare US Biotechnology
245 Berkeley Lights, Inc. $168.7 M

(Jan. 1, 2023)

 United States US Healthcare US Biotechnology
246 Alector, Inc. $167.0 M United States US Healthcare US Biotechnology
247 Coherus BioSciences, Inc. $165.6 M United States US Healthcare US Biotechnology
248 Mind Medicine MindMed, Inc. $164.0 M

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology
249 La Jolla Pharmaceutical Company $155.1 M

(Aug. 1, 2022)

 United States US Healthcare US Biotechnology
250 Sangamo Therapeutics, Inc. $147.6 M United States US Healthcare US Biotechnology
251 Checkpoint Therapeutics, Inc. $146.5 M

(Jan. 1, 2025)

 United States US Healthcare US Biotechnology
252 Codexis, Inc. $145.4 M United States US Healthcare US Biotechnology
253 Mersana Therapeutics, Inc. $145.2 M United States US Healthcare US Biotechnology
254 Black Diamond Therapeutics, Inc. $141.9 M United States US Healthcare US Biotechnology
255 Talaris Therapeutics, Inc. $137.4 M

(July 1, 2023)

 United States US Healthcare US Biotechnology
256 Seres Therapeutics, Inc. $137.1 M United States US Healthcare US Biotechnology
257 Strongbridge Biopharma plc $135.7 M

(Oct. 1, 2021)

 United States US Healthcare US Biotechnology
258 Selecta Biosciences, Inc. $135.2 M

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology
259 Anika Therapeutics, Inc. $134.8 M United States US Healthcare US Biotechnology
260 Nkarta, Inc. $132.8 M United States US Healthcare US Biotechnology
261 Spero Therapeutics, Inc. $132.4 M United States US Healthcare US Biotechnology
262 G1 Therapeutics, Inc. $131.2 M

(July 1, 2024)

 United States US Healthcare US Biotechnology
263 Sesen Bio, Inc. $128.0 M

(March 1, 2023)

 United States US Healthcare US Biotechnology
264 Paratek Pharmaceuticals, Inc. $125.7 M

(July 1, 2023)

 United States US Healthcare US Biotechnology
265 Ovid Therapeutics Inc. $125.3 M United States US Healthcare US Biotechnology
266 Fortress Biotech, Inc. $125.1 M United States US Healthcare US Biotechnology
267 Karyopharm Therapeutics Inc. $122.6 M United States US Healthcare US Biotechnology
268 Eledon Pharmaceuticals, Inc. $121.6 M United States US Healthcare US Biotechnology
269 Graybug Vision, Inc. $121.0 M

(May 1, 2023)

 United States US Healthcare US Biotechnology
270 Progenity, Inc. $120.7 M

(July 1, 2024)

 United States US Healthcare US Biotechnology

Top Biotechnology Companies from the United States as of Jan. 01, 2026

241. Cardiff Oncology, Inc.

Company Profile: Cardiff Oncology, Inc.
Market Cap (USD): $179.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

242. Harpoon Therapeutics, Inc.

Company Profile: Harpoon Therapeutics, Inc.
Market Cap (USD): $178.6 M (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

243. Arcturus Therapeutics Holdings Inc.

Company Profile: Arcturus Therapeutics Holdings Inc.
Market Cap (USD): $177.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

244. Prelude Therapeutics Incorporated

Company Profile: Prelude Therapeutics Incorporated
Market Cap (USD): $171.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

245. Berkeley Lights, Inc.

Company Profile: Berkeley Lights, Inc.
Market Cap (USD): $168.7 M (Jan. 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

246. Alector, Inc.

Company Profile: Alector, Inc.
Market Cap (USD): $167.0 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

247. Coherus BioSciences, Inc.

Company Profile: Coherus BioSciences, Inc.
Market Cap (USD): $165.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

248. Mind Medicine MindMed, Inc.

Company Profile: Mind Medicine MindMed, Inc.
Market Cap (USD): $164.0 M (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

249. La Jolla Pharmaceutical Company

Company Profile: La Jolla Pharmaceutical Company
Market Cap (USD): $155.1 M (Aug. 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

250. Sangamo Therapeutics, Inc.

Company Profile: Sangamo Therapeutics, Inc.
Market Cap (USD): $147.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

251. Checkpoint Therapeutics, Inc.

Company Profile: Checkpoint Therapeutics, Inc.
Market Cap (USD): $146.5 M (Jan. 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

252. Codexis, Inc.

Company Profile: Codexis, Inc.
Market Cap (USD): $145.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

253. Mersana Therapeutics, Inc.

Company Profile: Mersana Therapeutics, Inc.
Market Cap (USD): $145.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

254. Black Diamond Therapeutics, Inc.

Company Profile: Black Diamond Therapeutics, Inc.
Market Cap (USD): $141.9 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

255. Talaris Therapeutics, Inc.

Company Profile: Talaris Therapeutics, Inc.
Market Cap (USD): $137.4 M (July 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

256. Seres Therapeutics, Inc.

Company Profile: Seres Therapeutics, Inc.
Market Cap (USD): $137.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

257. Strongbridge Biopharma plc

Company Profile: Strongbridge Biopharma plc
Market Cap (USD): $135.7 M (Oct. 1, 2021)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

258. Selecta Biosciences, Inc.

Company Profile: Selecta Biosciences, Inc.
Market Cap (USD): $135.2 M (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

259. Anika Therapeutics, Inc.

Company Profile: Anika Therapeutics, Inc.
Market Cap (USD): $134.8 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

260. Nkarta, Inc.

Company Profile: Nkarta, Inc.
Market Cap (USD): $132.8 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

261. Spero Therapeutics, Inc.

Company Profile: Spero Therapeutics, Inc.
Market Cap (USD): $132.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

262. G1 Therapeutics, Inc.

Company Profile: G1 Therapeutics, Inc.
Market Cap (USD): $131.2 M (July 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

263. Sesen Bio, Inc.

Company Profile: Sesen Bio, Inc.
Market Cap (USD): $128.0 M (March 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

264. Paratek Pharmaceuticals, Inc.

Company Profile: Paratek Pharmaceuticals, Inc.
Market Cap (USD): $125.7 M (July 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

265. Ovid Therapeutics Inc.

Company Profile: Ovid Therapeutics Inc.
Market Cap (USD): $125.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

266. Fortress Biotech, Inc.

Company Profile: Fortress Biotech, Inc.
Market Cap (USD): $125.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

267. Karyopharm Therapeutics Inc.

Company Profile: Karyopharm Therapeutics Inc.
Market Cap (USD): $122.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

268. Eledon Pharmaceuticals, Inc.

Company Profile: Eledon Pharmaceuticals, Inc.
Market Cap (USD): $121.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

269. Graybug Vision, Inc.

Company Profile: Graybug Vision, Inc.
Market Cap (USD): $121.0 M (May 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

270. Progenity, Inc.

Company Profile: Progenity, Inc.
Market Cap (USD): $120.7 M (July 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

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