United States

Top 538 largest US Companies in the Biotechnology industry by Market Cap

This is the list of the largest public listed companies in the Biotechnology industry from the United States by market capitalization with links to their reference stock.

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Top Biotechnology Companies from the United States as of Jan. 01, 2026

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Rank Company Market Cap (USD) Country Sector Industry
121 Maravai LifeSciences Holdings, Inc. $1.25 B United States US Healthcare US Biotechnology
122 Xeris Biopharma Holdings, Inc. $1.22 B United States US Healthcare US Biotechnology
123 Omeros Corporation $1.16 B United States US Healthcare US Biotechnology
124 Novavax, Inc. $1.16 B United States US Healthcare US Biotechnology
125 Savara Inc. $1.15 B United States US Healthcare US Biotechnology
126 Phathom Pharmaceuticals, Inc. $1.12 B United States US Healthcare US Biotechnology
127 Sana Biotechnology, Inc. $1.12 B United States US Healthcare US Biotechnology
128 Inhibrx, Inc. $1.09 B United States US Healthcare US Biotechnology
129 Intellia Therapeutics, Inc. $1.07 B United States US Healthcare US Biotechnology
130 Xencor, Inc. $1.07 B United States US Healthcare US Biotechnology
131 UroGen Pharma Ltd. $1.06 B United States US Healthcare US Biotechnology
132 Alpine Immune Sciences, Inc. $1.03 B

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology
133 Forma Therapeutics Holdings, Inc. $1.01 B

(Oct. 1, 2022)

 United States US Healthcare US Biotechnology
134 Verve Therapeutics, Inc. $1.01 B

(July 1, 2025)

 United States US Healthcare US Biotechnology
135 Iovance Biotherapeutics, Inc. $1.00 B United States US Healthcare US Biotechnology
136 CorMedix Inc. $958.1 M United States US Healthcare US Biotechnology
137 Poseida Therapeutics, Inc. $925.9 M

(Jan. 1, 2025)

 United States US Healthcare US Biotechnology
138 Compass Therapeutics, Inc. $919.5 M United States US Healthcare US Biotechnology
139 Arbutus Biopharma Corporation $917.4 M United States US Healthcare US Biotechnology
140 Provention Bio, Inc. $912.0 M

(Jan. 1, 2023)

 United States US Healthcare US Biotechnology
141 Albireo Pharma, Inc. $910.7 M

(Jan. 1, 2023)

 United States US Healthcare US Biotechnology
142 Day One Biopharmaceuticals, Inc. $908.7 M United States US Healthcare US Biotechnology
143 Kura Oncology, Inc. $899.3 M United States US Healthcare US Biotechnology
144 Nektar Therapeutics $883.2 M United States US Healthcare US Biotechnology
145 RAPT Therapeutics, Inc. $882.6 M United States US Healthcare US Biotechnology
146 Esperion Therapeutics, Inc. $879.5 M United States US Healthcare US Biotechnology
147 Ambrx Biopharma, Inc. $878.1 M

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology
148 Geron Corporation $842.6 M United States US Healthcare US Biotechnology
149 Arvinas, Inc. $842.1 M United States US Healthcare US Biotechnology
150 Vir Biotechnology, Inc. $826.4 M United States US Healthcare US Biotechnology

Top Biotechnology Companies from the United States as of Jan. 01, 2026

121. Maravai LifeSciences Holdings, Inc.

Company Profile: Maravai LifeSciences Holdings, Inc.
Market Cap (USD): $1.25 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

122. Xeris Biopharma Holdings, Inc.

Company Profile: Xeris Biopharma Holdings, Inc.
Market Cap (USD): $1.22 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

123. Omeros Corporation

Company Profile: Omeros Corporation
Market Cap (USD): $1.16 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

124. Novavax, Inc.

Company Profile: Novavax, Inc.
Market Cap (USD): $1.16 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

125. Savara Inc.

Company Profile: Savara Inc.
Market Cap (USD): $1.15 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

126. Phathom Pharmaceuticals, Inc.

Company Profile: Phathom Pharmaceuticals, Inc.
Market Cap (USD): $1.12 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

127. Sana Biotechnology, Inc.

Company Profile: Sana Biotechnology, Inc.
Market Cap (USD): $1.12 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

128. Inhibrx, Inc.

Company Profile: Inhibrx, Inc.
Market Cap (USD): $1.09 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

129. Intellia Therapeutics, Inc.

Company Profile: Intellia Therapeutics, Inc.
Market Cap (USD): $1.07 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

130. Xencor, Inc.

Company Profile: Xencor, Inc.
Market Cap (USD): $1.07 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

131. UroGen Pharma Ltd.

Company Profile: UroGen Pharma Ltd.
Market Cap (USD): $1.06 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

132. Alpine Immune Sciences, Inc.

Company Profile: Alpine Immune Sciences, Inc.
Market Cap (USD): $1.03 B (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

133. Forma Therapeutics Holdings, Inc.

Company Profile: Forma Therapeutics Holdings, Inc.
Market Cap (USD): $1.01 B (Oct. 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

134. Verve Therapeutics, Inc.

Company Profile: Verve Therapeutics, Inc.
Market Cap (USD): $1.01 B (July 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

135. Iovance Biotherapeutics, Inc.

Company Profile: Iovance Biotherapeutics, Inc.
Market Cap (USD): $1.00 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

136. CorMedix Inc.

Company Profile: CorMedix Inc.
Market Cap (USD): $958.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

137. Poseida Therapeutics, Inc.

Company Profile: Poseida Therapeutics, Inc.
Market Cap (USD): $925.9 M (Jan. 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

138. Compass Therapeutics, Inc.

Company Profile: Compass Therapeutics, Inc.
Market Cap (USD): $919.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

139. Arbutus Biopharma Corporation

Company Profile: Arbutus Biopharma Corporation
Market Cap (USD): $917.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

140. Provention Bio, Inc.

Company Profile: Provention Bio, Inc.
Market Cap (USD): $912.0 M (Jan. 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

141. Albireo Pharma, Inc.

Company Profile: Albireo Pharma, Inc.
Market Cap (USD): $910.7 M (Jan. 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

142. Day One Biopharmaceuticals, Inc.

Company Profile: Day One Biopharmaceuticals, Inc.
Market Cap (USD): $908.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

143. Kura Oncology, Inc.

Company Profile: Kura Oncology, Inc.
Market Cap (USD): $899.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

144. Nektar Therapeutics

Company Profile: Nektar Therapeutics
Market Cap (USD): $883.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

145. RAPT Therapeutics, Inc.

Company Profile: RAPT Therapeutics, Inc.
Market Cap (USD): $882.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

146. Esperion Therapeutics, Inc.

Company Profile: Esperion Therapeutics, Inc.
Market Cap (USD): $879.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

147. Ambrx Biopharma, Inc.

Company Profile: Ambrx Biopharma, Inc.
Market Cap (USD): $878.1 M (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

148. Geron Corporation

Company Profile: Geron Corporation
Market Cap (USD): $842.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

149. Arvinas, Inc.

Company Profile: Arvinas, Inc.
Market Cap (USD): $842.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

150. Vir Biotechnology, Inc.

Company Profile: Vir Biotechnology, Inc.
Market Cap (USD): $826.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

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