United States

Top 538 largest US Companies in the Biotechnology industry by Market Cap

This is the list of the largest public listed companies in the Biotechnology industry from the United States by market capitalization with links to their reference stock.

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Top Biotechnology Companies from the United States as of Jul. 01, 2025

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Rank Company Market Cap (USD) Country Sector Industry
121 Ambrx Biopharma, Inc. $878.1 M

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology
122 CorMedix Inc. $864.9 M United States US Healthcare US Biotechnology
123 Cogent Biosciences, Inc. $863.0 M United States US Healthcare US Biotechnology
124 Avid Bioservices, Inc. $796.3 M

(Jan. 1, 2025)

 United States US Healthcare US Biotechnology
125 Intercept Pharmaceuticals, Inc. $794.7 M

(Nov. 1, 2023)

 United States US Healthcare US Biotechnology
126 Syndax Pharmaceuticals, Inc. $774.4 M United States US Healthcare US Biotechnology
127 Immunome, Inc. $769.2 M United States US Healthcare US Biotechnology
128 Xeris Biopharma Holdings, Inc. $760.7 M United States US Healthcare US Biotechnology
129 Vir Biotechnology, Inc. $747.9 M United States US Healthcare US Biotechnology
130 CTI BioPharma Corp. $737.3 M

(Jan. 1, 2023)

 United States US Healthcare US Biotechnology
131 Replimune Group, Inc. $726.2 M United States US Healthcare US Biotechnology
132 Trevi Therapeutics, Inc. $724.4 M United States US Healthcare US Biotechnology
133 Sana Biotechnology, Inc. $719.5 M United States US Healthcare US Biotechnology
134 Nuvation Bio, Inc. $711.1 M United States US Healthcare US Biotechnology
135 AnaptysBio, Inc. $697.8 M United States US Healthcare US Biotechnology
136 Day One Biopharmaceuticals, Inc. $689.3 M United States US Healthcare US Biotechnology
137 EyePoint Pharmaceuticals, Inc. $668.8 M United States US Healthcare US Biotechnology
138 Taysha Gene Therapies, Inc. $640.7 M United States US Healthcare US Biotechnology
139 Stoke Therapeutics, Inc. $626.8 M United States US Healthcare US Biotechnology
140 UroGen Pharma Ltd. $626.1 M United States US Healthcare US Biotechnology
141 Phathom Pharmaceuticals, Inc. $622.7 M United States US Healthcare US Biotechnology
142 Relay Therapeutics, Inc. $622.3 M United States US Healthcare US Biotechnology
143 Arbutus Biopharma Corporation $620.5 M United States US Healthcare US Biotechnology
144 ChromaDex Corporation $611.9 M United States US Healthcare US Biotechnology
145 MeiraGTx Holdings plc $603.5 M United States US Healthcare US Biotechnology
146 Xencor, Inc. $599.3 M United States US Healthcare US Biotechnology
147 KalVista Pharmaceuticals, Inc. $595.6 M United States US Healthcare US Biotechnology
148 Iovance Biotherapeutics, Inc. $584.4 M United States US Healthcare US Biotechnology
149 Arvinas, Inc. $580.3 M United States US Healthcare US Biotechnology
150 BioDelivery Sciences International, Inc. $577.1 M

(March 1, 2022)

 United States US Healthcare US Biotechnology

Top Biotechnology Companies from the United States as of Jul. 01, 2025

121. Ambrx Biopharma, Inc.

Company Profile: Ambrx Biopharma, Inc.
Market Cap (USD): $878.1 M (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

122. CorMedix Inc.

Company Profile: CorMedix Inc.
Market Cap (USD): $864.9 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

123. Cogent Biosciences, Inc.

Company Profile: Cogent Biosciences, Inc.
Market Cap (USD): $863.0 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

124. Avid Bioservices, Inc.

Company Profile: Avid Bioservices, Inc.
Market Cap (USD): $796.3 M (Jan. 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

125. Intercept Pharmaceuticals, Inc.

Company Profile: Intercept Pharmaceuticals, Inc.
Market Cap (USD): $794.7 M (Nov. 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

126. Syndax Pharmaceuticals, Inc.

Company Profile: Syndax Pharmaceuticals, Inc.
Market Cap (USD): $774.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

127. Immunome, Inc.

Company Profile: Immunome, Inc.
Market Cap (USD): $769.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

128. Xeris Biopharma Holdings, Inc.

Company Profile: Xeris Biopharma Holdings, Inc.
Market Cap (USD): $760.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

129. Vir Biotechnology, Inc.

Company Profile: Vir Biotechnology, Inc.
Market Cap (USD): $747.9 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

130. CTI BioPharma Corp.

Company Profile: CTI BioPharma Corp.
Market Cap (USD): $737.3 M (Jan. 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

131. Replimune Group, Inc.

Company Profile: Replimune Group, Inc.
Market Cap (USD): $726.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

132. Trevi Therapeutics, Inc.

Company Profile: Trevi Therapeutics, Inc.
Market Cap (USD): $724.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

133. Sana Biotechnology, Inc.

Company Profile: Sana Biotechnology, Inc.
Market Cap (USD): $719.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

134. Nuvation Bio, Inc.

Company Profile: Nuvation Bio, Inc.
Market Cap (USD): $711.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

135. AnaptysBio, Inc.

Company Profile: AnaptysBio, Inc.
Market Cap (USD): $697.8 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

136. Day One Biopharmaceuticals, Inc.

Company Profile: Day One Biopharmaceuticals, Inc.
Market Cap (USD): $689.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

137. EyePoint Pharmaceuticals, Inc.

Company Profile: EyePoint Pharmaceuticals, Inc.
Market Cap (USD): $668.8 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

138. Taysha Gene Therapies, Inc.

Company Profile: Taysha Gene Therapies, Inc.
Market Cap (USD): $640.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

139. Stoke Therapeutics, Inc.

Company Profile: Stoke Therapeutics, Inc.
Market Cap (USD): $626.8 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

140. UroGen Pharma Ltd.

Company Profile: UroGen Pharma Ltd.
Market Cap (USD): $626.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

141. Phathom Pharmaceuticals, Inc.

Company Profile: Phathom Pharmaceuticals, Inc.
Market Cap (USD): $622.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

142. Relay Therapeutics, Inc.

Company Profile: Relay Therapeutics, Inc.
Market Cap (USD): $622.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

143. Arbutus Biopharma Corporation

Company Profile: Arbutus Biopharma Corporation
Market Cap (USD): $620.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

144. ChromaDex Corporation

Company Profile: ChromaDex Corporation
Market Cap (USD): $611.9 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

145. MeiraGTx Holdings plc

Company Profile: MeiraGTx Holdings plc
Market Cap (USD): $603.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

146. Xencor, Inc.

Company Profile: Xencor, Inc.
Market Cap (USD): $599.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

147. KalVista Pharmaceuticals, Inc.

Company Profile: KalVista Pharmaceuticals, Inc.
Market Cap (USD): $595.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

148. Iovance Biotherapeutics, Inc.

Company Profile: Iovance Biotherapeutics, Inc.
Market Cap (USD): $584.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

149. Arvinas, Inc.

Company Profile: Arvinas, Inc.
Market Cap (USD): $580.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

150. BioDelivery Sciences International, Inc.

Company Profile: BioDelivery Sciences International, Inc.
Market Cap (USD): $577.1 M (March 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

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