United States

Top 538 largest US Companies in the Biotechnology industry by Market Cap

This is the list of the largest public listed companies in the Biotechnology industry from the United States by market capitalization with links to their reference stock.

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Top Biotechnology Companies from the United States as of Jan. 01, 2026

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Rank Company Market Cap (USD) Country Sector Industry
91 Recursion Pharmaceuticals, Inc. $2.19 B United States US Healthcare US Biotechnology
92 Harmony Biosciences Holdings, Inc. $2.15 B United States US Healthcare US Biotechnology
93 Olema Pharmaceuticals, Inc. $2.03 B United States US Healthcare US Biotechnology
94 ImmunityBio, Inc. $1.99 B United States US Healthcare US Biotechnology
95 Syndax Pharmaceuticals, Inc. $1.85 B United States US Healthcare US Biotechnology
96 Nurix Therapeutics, Inc. $1.83 B United States US Healthcare US Biotechnology
97 Dynavax Technologies Corporation $1.81 B United States US Healthcare US Biotechnology
98 Vericel Corporation $1.80 B United States US Healthcare US Biotechnology
99 Celldex Therapeutics, Inc. $1.79 B United States US Healthcare US Biotechnology
100 Stoke Therapeutics, Inc. $1.76 B United States US Healthcare US Biotechnology
101 MannKind Corporation $1.72 B United States US Healthcare US Biotechnology
102 Biohaven Pharmaceutical Holding Company Ltd. $1.68 B

(July 1, 2023)

 United States US Healthcare US Biotechnology
103 Kadmon Holdings, Inc. $1.63 B

(Nov. 1, 2021)

 United States US Healthcare US Biotechnology
104 Morphic Holding, Inc. $1.59 B

(July 1, 2024)

 United States US Healthcare US Biotechnology
105 Kodiak Sciences Inc. $1.59 B United States US Healthcare US Biotechnology
106 Agios Pharmaceuticals, Inc. $1.58 B United States US Healthcare US Biotechnology
107 BioCryst Pharmaceuticals, Inc. $1.58 B United States US Healthcare US Biotechnology
108 Capricor Therapeutics, Inc. $1.54 B United States US Healthcare US Biotechnology
109 Trevi Therapeutics, Inc. $1.52 B United States US Healthcare US Biotechnology
110 Precigen, Inc. $1.51 B United States US Healthcare US Biotechnology
111 Ardelyx, Inc. $1.49 B United States US Healthcare US Biotechnology
112 Zogenix, Inc. $1.49 B

(March 1, 2022)

 United States US Healthcare US Biotechnology
113 Innoviva, Inc. $1.49 B United States US Healthcare US Biotechnology
114 89bio, Inc. $1.48 B

(July 1, 2025)

 United States US Healthcare US Biotechnology
115 EyePoint Pharmaceuticals, Inc. $1.45 B United States US Healthcare US Biotechnology
116 Taysha Gene Therapies, Inc. $1.44 B United States US Healthcare US Biotechnology
117 Relay Therapeutics, Inc. $1.42 B United States US Healthcare US Biotechnology
118 Certara, Inc. $1.39 B United States US Healthcare US Biotechnology
119 Longboard Pharmaceuticals, Inc. $1.36 B

(July 1, 2024)

 United States US Healthcare US Biotechnology
120 AnaptysBio, Inc. $1.26 B United States US Healthcare US Biotechnology

Top Biotechnology Companies from the United States as of Jan. 01, 2026

91. Recursion Pharmaceuticals, Inc.

Company Profile: Recursion Pharmaceuticals, Inc.
Market Cap (USD): $2.19 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

92. Harmony Biosciences Holdings, Inc.

Company Profile: Harmony Biosciences Holdings, Inc.
Market Cap (USD): $2.15 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

93. Olema Pharmaceuticals, Inc.

Company Profile: Olema Pharmaceuticals, Inc.
Market Cap (USD): $2.03 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

94. ImmunityBio, Inc.

Company Profile: ImmunityBio, Inc.
Market Cap (USD): $1.99 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

95. Syndax Pharmaceuticals, Inc.

Company Profile: Syndax Pharmaceuticals, Inc.
Market Cap (USD): $1.85 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

96. Nurix Therapeutics, Inc.

Company Profile: Nurix Therapeutics, Inc.
Market Cap (USD): $1.83 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

97. Dynavax Technologies Corporation

Company Profile: Dynavax Technologies Corporation
Market Cap (USD): $1.81 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

98. Vericel Corporation

Company Profile: Vericel Corporation
Market Cap (USD): $1.80 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

99. Celldex Therapeutics, Inc.

Company Profile: Celldex Therapeutics, Inc.
Market Cap (USD): $1.79 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

100. Stoke Therapeutics, Inc.

Company Profile: Stoke Therapeutics, Inc.
Market Cap (USD): $1.76 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

101. MannKind Corporation

Company Profile: MannKind Corporation
Market Cap (USD): $1.72 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

102. Biohaven Pharmaceutical Holding Company Ltd.

Company Profile: Biohaven Pharmaceutical Holding Company Ltd.
Market Cap (USD): $1.68 B (July 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

103. Kadmon Holdings, Inc.

Company Profile: Kadmon Holdings, Inc.
Market Cap (USD): $1.63 B (Nov. 1, 2021)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

104. Morphic Holding, Inc.

Company Profile: Morphic Holding, Inc.
Market Cap (USD): $1.59 B (July 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

105. Kodiak Sciences Inc.

Company Profile: Kodiak Sciences Inc.
Market Cap (USD): $1.59 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

106. Agios Pharmaceuticals, Inc.

Company Profile: Agios Pharmaceuticals, Inc.
Market Cap (USD): $1.58 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

107. BioCryst Pharmaceuticals, Inc.

Company Profile: BioCryst Pharmaceuticals, Inc.
Market Cap (USD): $1.58 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

108. Capricor Therapeutics, Inc.

Company Profile: Capricor Therapeutics, Inc.
Market Cap (USD): $1.54 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

109. Trevi Therapeutics, Inc.

Company Profile: Trevi Therapeutics, Inc.
Market Cap (USD): $1.52 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

110. Precigen, Inc.

Company Profile: Precigen, Inc.
Market Cap (USD): $1.51 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

111. Ardelyx, Inc.

Company Profile: Ardelyx, Inc.
Market Cap (USD): $1.49 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

112. Zogenix, Inc.

Company Profile: Zogenix, Inc.
Market Cap (USD): $1.49 B (March 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

113. Innoviva, Inc.

Company Profile: Innoviva, Inc.
Market Cap (USD): $1.49 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

114. 89bio, Inc.

Company Profile: 89bio, Inc.
Market Cap (USD): $1.48 B (July 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

115. EyePoint Pharmaceuticals, Inc.

Company Profile: EyePoint Pharmaceuticals, Inc.
Market Cap (USD): $1.45 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

116. Taysha Gene Therapies, Inc.

Company Profile: Taysha Gene Therapies, Inc.
Market Cap (USD): $1.44 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

117. Relay Therapeutics, Inc.

Company Profile: Relay Therapeutics, Inc.
Market Cap (USD): $1.42 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

118. Certara, Inc.

Company Profile: Certara, Inc.
Market Cap (USD): $1.39 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

119. Longboard Pharmaceuticals, Inc.

Company Profile: Longboard Pharmaceuticals, Inc.
Market Cap (USD): $1.36 B (July 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

120. AnaptysBio, Inc.

Company Profile: AnaptysBio, Inc.
Market Cap (USD): $1.26 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

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