United States

Top 538 largest US Companies in the Biotechnology industry by Market Cap

This is the list of the largest public listed companies in the Biotechnology industry from the United States by market capitalization with links to their reference stock.

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Top Biotechnology Companies from the United States as of Jan. 01, 2025

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Rank Company Market Cap (USD) Country Sector Industry
31 Legend Biotech Corporation $5.78 B United States US Healthcare US Biotechnology
32 Cytokinetics, Incorporated $5.65 B United States US Healthcare US Biotechnology
33 Ionis Pharmaceuticals, Inc. $5.16 B United States US Healthcare US Biotechnology
34 Axsome Therapeutics, Inc. $5.00 B United States US Healthcare US Biotechnology
35 Prometheus Biosciences, Inc. $4.95 B

(Jan. 1, 2023)

 United States US Healthcare US Biotechnology
36 Global Blood Therapeutics, Inc. $4.62 B

(Oct. 1, 2022)

 United States US Healthcare US Biotechnology
37 TG Therapeutics, Inc. $4.52 B United States US Healthcare US Biotechnology
38 Krystal Biotech, Inc. $4.46 B United States US Healthcare US Biotechnology
39 Scholar Rock Holding Corporation $4.25 B United States US Healthcare US Biotechnology
40 Reata Pharmaceuticals, Inc. $4.19 B

(July 1, 2023)

 United States US Healthcare US Biotechnology
41 Mirati Therapeutics, Inc. $4.15 B

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology
42 Ultragenyx Pharmaceutical Inc. $4.07 B United States US Healthcare US Biotechnology
43 Immunovant, Inc. $3.96 B United States US Healthcare US Biotechnology
44 ADMA Biologics, Inc. $3.92 B United States US Healthcare US Biotechnology
45 Viking Therapeutics, Inc. $3.89 B United States US Healthcare US Biotechnology
46 Turning Point Therapeutics, Inc. $3.81 B

(Aug. 1, 2022)

 United States US Healthcare US Biotechnology
47 ChemoCentryx, Inc. $3.74 B

(Oct. 1, 2022)

 United States US Healthcare US Biotechnology
48 Apellis Pharmaceuticals, Inc. $3.73 B United States US Healthcare US Biotechnology
49 Crinetics Pharmaceuticals, Inc. $3.64 B United States US Healthcare US Biotechnology
50 PTC Therapeutics, Inc. $3.56 B United States US Healthcare US Biotechnology
51 Rhythm Pharmaceuticals, Inc. $3.55 B United States US Healthcare US Biotechnology
52 ImmunityBio, Inc. $3.46 B United States US Healthcare US Biotechnology
53 Veracyte, Inc. $3.40 B United States US Healthcare US Biotechnology
54 Avidity Biosciences, Inc. $3.37 B United States US Healthcare US Biotechnology
55 Denali Therapeutics Inc. $3.35 B United States US Healthcare US Biotechnology
56 VitaSpring Biomedical Co. Ltd $3.30 B United States US Healthcare US Biotechnology
57 Recursion Pharmaceuticals, Inc. $3.12 B United States US Healthcare US Biotechnology
58 ACADIA Pharmaceuticals Inc. $3.11 B United States US Healthcare US Biotechnology
59 Edgewise Therapeutics, Inc. $3.09 B United States US Healthcare US Biotechnology
60 Vera Therapeutics, Inc. $3.07 B United States US Healthcare US Biotechnology

Top Biotechnology Companies from the United States as of Jan. 01, 2025

31. Legend Biotech Corporation

Company Profile: Legend Biotech Corporation
Market Cap (USD): $5.78 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

32. Cytokinetics, Incorporated

Company Profile: Cytokinetics, Incorporated
Market Cap (USD): $5.65 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

33. Ionis Pharmaceuticals, Inc.

Company Profile: Ionis Pharmaceuticals, Inc.
Market Cap (USD): $5.16 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

34. Axsome Therapeutics, Inc.

Company Profile: Axsome Therapeutics, Inc.
Market Cap (USD): $5.00 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

35. Prometheus Biosciences, Inc.

Company Profile: Prometheus Biosciences, Inc.
Market Cap (USD): $4.95 B (Jan. 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

36. Global Blood Therapeutics, Inc.

Company Profile: Global Blood Therapeutics, Inc.
Market Cap (USD): $4.62 B (Oct. 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

37. TG Therapeutics, Inc.

Company Profile: TG Therapeutics, Inc.
Market Cap (USD): $4.52 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

38. Krystal Biotech, Inc.

Company Profile: Krystal Biotech, Inc.
Market Cap (USD): $4.46 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

39. Scholar Rock Holding Corporation

Company Profile: Scholar Rock Holding Corporation
Market Cap (USD): $4.25 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

40. Reata Pharmaceuticals, Inc.

Company Profile: Reata Pharmaceuticals, Inc.
Market Cap (USD): $4.19 B (July 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

41. Mirati Therapeutics, Inc.

Company Profile: Mirati Therapeutics, Inc.
Market Cap (USD): $4.15 B (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

42. Ultragenyx Pharmaceutical Inc.

Company Profile: Ultragenyx Pharmaceutical Inc.
Market Cap (USD): $4.07 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

43. Immunovant, Inc.

Company Profile: Immunovant, Inc.
Market Cap (USD): $3.96 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

44. ADMA Biologics, Inc.

Company Profile: ADMA Biologics, Inc.
Market Cap (USD): $3.92 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

45. Viking Therapeutics, Inc.

Company Profile: Viking Therapeutics, Inc.
Market Cap (USD): $3.89 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

46. Turning Point Therapeutics, Inc.

Company Profile: Turning Point Therapeutics, Inc.
Market Cap (USD): $3.81 B (Aug. 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

47. ChemoCentryx, Inc.

Company Profile: ChemoCentryx, Inc.
Market Cap (USD): $3.74 B (Oct. 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

48. Apellis Pharmaceuticals, Inc.

Company Profile: Apellis Pharmaceuticals, Inc.
Market Cap (USD): $3.73 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

49. Crinetics Pharmaceuticals, Inc.

Company Profile: Crinetics Pharmaceuticals, Inc.
Market Cap (USD): $3.64 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

50. PTC Therapeutics, Inc.

Company Profile: PTC Therapeutics, Inc.
Market Cap (USD): $3.56 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

51. Rhythm Pharmaceuticals, Inc.

Company Profile: Rhythm Pharmaceuticals, Inc.
Market Cap (USD): $3.55 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

52. ImmunityBio, Inc.

Company Profile: ImmunityBio, Inc.
Market Cap (USD): $3.46 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

53. Veracyte, Inc.

Company Profile: Veracyte, Inc.
Market Cap (USD): $3.40 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

54. Avidity Biosciences, Inc.

Company Profile: Avidity Biosciences, Inc.
Market Cap (USD): $3.37 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

55. Denali Therapeutics Inc.

Company Profile: Denali Therapeutics Inc.
Market Cap (USD): $3.35 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

56. VitaSpring Biomedical Co. Ltd

Company Profile: VitaSpring Biomedical Co. Ltd
Market Cap (USD): $3.30 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

57. Recursion Pharmaceuticals, Inc.

Company Profile: Recursion Pharmaceuticals, Inc.
Market Cap (USD): $3.12 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

58. ACADIA Pharmaceuticals Inc.

Company Profile: ACADIA Pharmaceuticals Inc.
Market Cap (USD): $3.11 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

59. Edgewise Therapeutics, Inc.

Company Profile: Edgewise Therapeutics, Inc.
Market Cap (USD): $3.09 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

60. Vera Therapeutics, Inc.

Company Profile: Vera Therapeutics, Inc.
Market Cap (USD): $3.07 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

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