United States

Top 1000 largest US Companies in the Healthcare sector by Market Cap

This is the list of the largest public listed companies in the Healthcare sector from the United States by market capitalization with links to their reference stock and industry.

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Top Healthcare Companies from the United States as of Jan. 01, 2026

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Rank Company Market Cap (USD) Country Sector Industry
301 Xencor, Inc. $1.07 B United States US Healthcare US Biotechnology
302 UroGen Pharma Ltd. $1.06 B United States US Healthcare US Biotechnology
303 Alpine Immune Sciences, Inc. $1.03 B

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology
304 CareDx, Inc $1.02 B United States US Healthcare US Diagnostics & Research
305 OPKO Health, Inc. $1.01 B United States US Healthcare US Diagnostics & Research
306 Forma Therapeutics Holdings, Inc. $1.01 B

(Oct. 1, 2022)

 United States US Healthcare US Biotechnology
307 Verve Therapeutics, Inc. $1.01 B

(July 1, 2025)

 United States US Healthcare US Biotechnology
308 Iovance Biotherapeutics, Inc. $1.00 B United States US Healthcare US Biotechnology
309 Phreesia, Inc. $982.7 M United States US Healthcare US Health Information Services
310 The Pennant Group, Inc. $962.7 M United States US Healthcare US Medical Care Facilities
311 MiMedx Group, Inc. $959.7 M United States US Healthcare US Medical Devices
312 CorMedix Inc. $958.1 M United States US Healthcare US Biotechnology
313 GoodRx Holdings, Inc. $955.5 M United States US Healthcare US Health Information Services
314 Antares Pharma, Inc. $955.1 M

(May 1, 2022)

 United States US Healthcare US Medical Instruments & Supplies
315 Intersect ENT, Inc. $954.9 M

(May 1, 2022)

 United States US Healthcare US Medical Devices
316 Butterfly Network, Inc. $947.3 M United States US Healthcare US Medical Devices
317 Integra LifeSciences Holdings Corporation $935.7 M United States US Healthcare US Medical Devices
318 Poseida Therapeutics, Inc. $925.9 M

(Jan. 1, 2025)

 United States US Healthcare US Biotechnology
319 Compass Therapeutics, Inc. $919.5 M United States US Healthcare US Biotechnology
320 Arbutus Biopharma Corporation $917.4 M United States US Healthcare US Biotechnology
321 Provention Bio, Inc. $912.0 M

(Jan. 1, 2023)

 United States US Healthcare US Biotechnology
322 Albireo Pharma, Inc. $910.7 M

(Jan. 1, 2023)

 United States US Healthcare US Biotechnology
323 Day One Biopharmaceuticals, Inc. $908.7 M United States US Healthcare US Biotechnology
324 Pulse Biosciences, Inc. $907.4 M United States US Healthcare US Medical Instruments & Supplies
325 Kura Oncology, Inc. $899.3 M United States US Healthcare US Biotechnology
326 Nektar Therapeutics $883.2 M United States US Healthcare US Biotechnology
327 RAPT Therapeutics, Inc. $882.6 M United States US Healthcare US Biotechnology
328 Esperion Therapeutics, Inc. $879.5 M United States US Healthcare US Biotechnology
329 Ambrx Biopharma, Inc. $878.1 M

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology
330 SI-BONE, Inc. $858.7 M United States US Healthcare US Medical Devices

Top Healthcare Companies from the United States as of Jan. 01, 2026

301. Xencor, Inc.

Company Profile: Xencor, Inc.
Market Cap (USD): $1.07 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

302. UroGen Pharma Ltd.

Company Profile: UroGen Pharma Ltd.
Market Cap (USD): $1.06 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

303. Alpine Immune Sciences, Inc.

Company Profile: Alpine Immune Sciences, Inc.
Market Cap (USD): $1.03 B (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

304. CareDx, Inc

Company Profile: CareDx, Inc
Market Cap (USD): $1.02 B
Country: United States
Sector: US Healthcare
Industry: US Diagnostics & Research

305. OPKO Health, Inc.

Company Profile: OPKO Health, Inc.
Market Cap (USD): $1.01 B
Country: United States
Sector: US Healthcare
Industry: US Diagnostics & Research

306. Forma Therapeutics Holdings, Inc.

Company Profile: Forma Therapeutics Holdings, Inc.
Market Cap (USD): $1.01 B (Oct. 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

307. Verve Therapeutics, Inc.

Company Profile: Verve Therapeutics, Inc.
Market Cap (USD): $1.01 B (July 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

308. Iovance Biotherapeutics, Inc.

Company Profile: Iovance Biotherapeutics, Inc.
Market Cap (USD): $1.00 B
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

309. Phreesia, Inc.

Company Profile: Phreesia, Inc.
Market Cap (USD): $982.7 M
Country: United States
Sector: US Healthcare
Industry: US Health Information Services

310. The Pennant Group, Inc.

Company Profile: The Pennant Group, Inc.
Market Cap (USD): $962.7 M
Country: United States
Sector: US Healthcare
Industry: US Medical Care Facilities

311. MiMedx Group, Inc.

Company Profile: MiMedx Group, Inc.
Market Cap (USD): $959.7 M
Country: United States
Sector: US Healthcare
Industry: US Medical Devices

312. CorMedix Inc.

Company Profile: CorMedix Inc.
Market Cap (USD): $958.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

313. GoodRx Holdings, Inc.

Company Profile: GoodRx Holdings, Inc.
Market Cap (USD): $955.5 M
Country: United States
Sector: US Healthcare
Industry: US Health Information Services

314. Antares Pharma, Inc.

Company Profile: Antares Pharma, Inc.
Market Cap (USD): $955.1 M (May 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Medical Instruments & Supplies

315. Intersect ENT, Inc.

Company Profile: Intersect ENT, Inc.
Market Cap (USD): $954.9 M (May 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Medical Devices

316. Butterfly Network, Inc.

Company Profile: Butterfly Network, Inc.
Market Cap (USD): $947.3 M
Country: United States
Sector: US Healthcare
Industry: US Medical Devices

317. Integra LifeSciences Holdings Corporation

Company Profile: Integra LifeSciences Holdings Corporation
Market Cap (USD): $935.7 M
Country: United States
Sector: US Healthcare
Industry: US Medical Devices

318. Poseida Therapeutics, Inc.

Company Profile: Poseida Therapeutics, Inc.
Market Cap (USD): $925.9 M (Jan. 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

319. Compass Therapeutics, Inc.

Company Profile: Compass Therapeutics, Inc.
Market Cap (USD): $919.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

320. Arbutus Biopharma Corporation

Company Profile: Arbutus Biopharma Corporation
Market Cap (USD): $917.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

321. Provention Bio, Inc.

Company Profile: Provention Bio, Inc.
Market Cap (USD): $912.0 M (Jan. 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

322. Albireo Pharma, Inc.

Company Profile: Albireo Pharma, Inc.
Market Cap (USD): $910.7 M (Jan. 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

323. Day One Biopharmaceuticals, Inc.

Company Profile: Day One Biopharmaceuticals, Inc.
Market Cap (USD): $908.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

324. Pulse Biosciences, Inc.

Company Profile: Pulse Biosciences, Inc.
Market Cap (USD): $907.4 M
Country: United States
Sector: US Healthcare
Industry: US Medical Instruments & Supplies

325. Kura Oncology, Inc.

Company Profile: Kura Oncology, Inc.
Market Cap (USD): $899.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

326. Nektar Therapeutics

Company Profile: Nektar Therapeutics
Market Cap (USD): $883.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

327. RAPT Therapeutics, Inc.

Company Profile: RAPT Therapeutics, Inc.
Market Cap (USD): $882.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

328. Esperion Therapeutics, Inc.

Company Profile: Esperion Therapeutics, Inc.
Market Cap (USD): $879.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

329. Ambrx Biopharma, Inc.

Company Profile: Ambrx Biopharma, Inc.
Market Cap (USD): $878.1 M (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

330. SI-BONE, Inc.

Company Profile: SI-BONE, Inc.
Market Cap (USD): $858.7 M
Country: United States
Sector: US Healthcare
Industry: US Medical Devices

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