United States

Top 1000 largest US Companies in the Healthcare sector by Market Cap

This is the list of the largest public listed companies in the Healthcare sector from the United States by market capitalization with links to their reference stock and industry.

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Top Healthcare Companies from the United States as of Jan. 01, 2026

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Rank Company Market Cap (USD) Country Sector Industry
391 Varex Imaging Corporation $485.7 M United States US Healthcare US Medical Devices
392 ChromaDex Corporation $483.3 M United States US Healthcare US Biotechnology
393 Bioventus, Inc. $482.9 M United States US Healthcare US Diagnostics & Research
394 Apollo Endosurgery, Inc. $467.9 M

(Jan. 1, 2023)

 United States US Healthcare US Medical Devices
395 Misonix, Inc. $462.5 M

(Oct. 1, 2021)

 United States US Healthcare US Medical Devices
396 Evolent Health, Inc. $451.1 M United States US Healthcare US Health Information Services
397 Cresco Labs, Inc. $450.3 M United States US Healthcare US Drug Manufacturers—Specialty & Generic
398 SIGA Technologies, Inc. $449.0 M United States US Healthcare US Biotechnology
399 Soliton, Inc. $444.9 M

(Dec. 1, 2021)

 United States US Healthcare US Medical Devices
400 OrthoPediatrics Corp. $440.4 M United States US Healthcare US Medical Devices
401 Eton Pharmaceuticals, Inc. $436.1 M United States US Healthcare US Biotechnology
402 Evolus, Inc. $435.6 M United States US Healthcare US Drug Manufacturers—Specialty & Generic
403 Community Health Systems, Inc. $434.4 M United States US Healthcare US Medical Care Facilities
404 Ocugen, Inc. $431.0 M United States US Healthcare US Biotechnology
405 Surmodics, Inc. $428.8 M

(July 1, 2025)

 United States US Healthcare US Medical Devices
406 Solid Biosciences Inc. $424.6 M United States US Healthcare US Drug Manufacturers—Specialty & Generic
407 4D Molecular Therapeutics, Inc. $418.2 M United States US Healthcare US Biotechnology
408 ClearPoint Neuro, Inc. $417.4 M United States US Healthcare US Medical Devices
409 Enanta Pharmaceuticals, Inc. $416.2 M United States US Healthcare US Biotechnology
410 National Research Corporation $415.8 M United States US Healthcare US Diagnostics & Research
411 Kindred Biosciences, Inc. $414.6 M

(July 1, 2021)

 United States US Healthcare US Drug Manufacturers—Specialty & Generic
412 Lexicon Pharmaceuticals, Inc. $414.3 M United States US Healthcare US Biotechnology
413 IMARA Inc. $413.7 M United States US Healthcare US Biotechnology
414 DiaMedica Therapeutics Inc. $413.0 M United States US Healthcare US Biotechnology
415 Akebia Therapeutics, Inc. $411.3 M United States US Healthcare US Biotechnology
416 PureTech Health plc $410.9 M United States US Healthcare US Biotechnology
417 Concert Pharmaceuticals, Inc. $401.9 M

(June 1, 2024)

 United States US Healthcare US Biotechnology
418 Northwest Biotherapeutics, Inc. $392.7 M United States US Healthcare US Biotechnology
419 iTeos Therapeutics, Inc. $389.6 M

(July 1, 2025)

 United States US Healthcare US Biotechnology
420 Revance Therapeutics, Inc. $381.0 M

(Jan. 1, 2025)

 United States US Healthcare US Biotechnology

Top Healthcare Companies from the United States as of Jan. 01, 2026

391. Varex Imaging Corporation

Company Profile: Varex Imaging Corporation
Market Cap (USD): $485.7 M
Country: United States
Sector: US Healthcare
Industry: US Medical Devices

392. ChromaDex Corporation

Company Profile: ChromaDex Corporation
Market Cap (USD): $483.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

393. Bioventus, Inc.

Company Profile: Bioventus, Inc.
Market Cap (USD): $482.9 M
Country: United States
Sector: US Healthcare
Industry: US Diagnostics & Research

394. Apollo Endosurgery, Inc.

Company Profile: Apollo Endosurgery, Inc.
Market Cap (USD): $467.9 M (Jan. 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Medical Devices

395. Misonix, Inc.

Company Profile: Misonix, Inc.
Market Cap (USD): $462.5 M (Oct. 1, 2021)
Country: United States
Sector: US Healthcare
Industry: US Medical Devices

396. Evolent Health, Inc.

Company Profile: Evolent Health, Inc.
Market Cap (USD): $451.1 M
Country: United States
Sector: US Healthcare
Industry: US Health Information Services

397. Cresco Labs, Inc.

Company Profile: Cresco Labs, Inc.
Market Cap (USD): $450.3 M
Country: United States
Sector: US Healthcare
Industry: US Drug Manufacturers—Specialty & Generic

398. SIGA Technologies, Inc.

Company Profile: SIGA Technologies, Inc.
Market Cap (USD): $449.0 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

399. Soliton, Inc.

Company Profile: Soliton, Inc.
Market Cap (USD): $444.9 M (Dec. 1, 2021)
Country: United States
Sector: US Healthcare
Industry: US Medical Devices

400. OrthoPediatrics Corp.

Company Profile: OrthoPediatrics Corp.
Market Cap (USD): $440.4 M
Country: United States
Sector: US Healthcare
Industry: US Medical Devices

401. Eton Pharmaceuticals, Inc.

Company Profile: Eton Pharmaceuticals, Inc.
Market Cap (USD): $436.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

402. Evolus, Inc.

Company Profile: Evolus, Inc.
Market Cap (USD): $435.6 M
Country: United States
Sector: US Healthcare
Industry: US Drug Manufacturers—Specialty & Generic

403. Community Health Systems, Inc.

Company Profile: Community Health Systems, Inc.
Market Cap (USD): $434.4 M
Country: United States
Sector: US Healthcare
Industry: US Medical Care Facilities

404. Ocugen, Inc.

Company Profile: Ocugen, Inc.
Market Cap (USD): $431.0 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

405. Surmodics, Inc.

Company Profile: Surmodics, Inc.
Market Cap (USD): $428.8 M (July 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Medical Devices

406. Solid Biosciences Inc.

Company Profile: Solid Biosciences Inc.
Market Cap (USD): $424.6 M
Country: United States
Sector: US Healthcare
Industry: US Drug Manufacturers—Specialty & Generic

407. 4D Molecular Therapeutics, Inc.

Company Profile: 4D Molecular Therapeutics, Inc.
Market Cap (USD): $418.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

408. ClearPoint Neuro, Inc.

Company Profile: ClearPoint Neuro, Inc.
Market Cap (USD): $417.4 M
Country: United States
Sector: US Healthcare
Industry: US Medical Devices

409. Enanta Pharmaceuticals, Inc.

Company Profile: Enanta Pharmaceuticals, Inc.
Market Cap (USD): $416.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

410. National Research Corporation

Company Profile: National Research Corporation
Market Cap (USD): $415.8 M
Country: United States
Sector: US Healthcare
Industry: US Diagnostics & Research

411. Kindred Biosciences, Inc.

Company Profile: Kindred Biosciences, Inc.
Market Cap (USD): $414.6 M (July 1, 2021)
Country: United States
Sector: US Healthcare
Industry: US Drug Manufacturers—Specialty & Generic

412. Lexicon Pharmaceuticals, Inc.

Company Profile: Lexicon Pharmaceuticals, Inc.
Market Cap (USD): $414.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

413. IMARA Inc.

Company Profile: IMARA Inc.
Market Cap (USD): $413.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

414. DiaMedica Therapeutics Inc.

Company Profile: DiaMedica Therapeutics Inc.
Market Cap (USD): $413.0 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

415. Akebia Therapeutics, Inc.

Company Profile: Akebia Therapeutics, Inc.
Market Cap (USD): $411.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

416. PureTech Health plc

Company Profile: PureTech Health plc
Market Cap (USD): $410.9 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

417. Concert Pharmaceuticals, Inc.

Company Profile: Concert Pharmaceuticals, Inc.
Market Cap (USD): $401.9 M (June 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

418. Northwest Biotherapeutics, Inc.

Company Profile: Northwest Biotherapeutics, Inc.
Market Cap (USD): $392.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

419. iTeos Therapeutics, Inc.

Company Profile: iTeos Therapeutics, Inc.
Market Cap (USD): $389.6 M (July 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

420. Revance Therapeutics, Inc.

Company Profile: Revance Therapeutics, Inc.
Market Cap (USD): $381.0 M (Jan. 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

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