United States

Top 1000 largest US Companies in the Healthcare sector by Market Cap

This is the list of the largest public listed companies in the Healthcare sector from the United States by market capitalization with links to their reference stock and industry.

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Top Healthcare Companies from the United States as of Jan. 01, 2026

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Rank Company Market Cap (USD) Country Sector Industry
451 Aldeyra Therapeutics, Inc. $281.0 M United States US Healthcare US Biotechnology
452 Viemed Healthcare, Inc. $280.0 M United States US Healthcare US Medical Devices
453 agilon health, Inc. $279.3 M United States US Healthcare US Medical Care Facilities
454 Frontage Holdings Corp $276.2 M United States US Healthcare US Biotechnology
455 Atea Pharmaceuticals, Inc. $271.9 M United States US Healthcare US Biotechnology
456 SmileDirectClub, Inc. $270.7 M

(July 1, 2023)

 United States US Healthcare US Medical Devices
457 Greenwich LifeSciences, Inc. $269.7 M United States US Healthcare US Biotechnology
458 Fennec Pharmaceuticals Inc. $262.3 M United States US Healthcare US Biotechnology
459 Galectin Therapeutics, Inc. $261.1 M United States US Healthcare US Biotechnology
460 Repro Med Systems, Inc. $259.9 M United States US Healthcare US Medical Instruments & Supplies
461 Inozyme Pharma, Inc. $258.2 M

(July 1, 2025)

 United States US Healthcare US Biotechnology
462 Vor Biopharma, Inc. $255.0 M United States US Healthcare US Biotechnology
463 Chiasma, Inc. $253.0 M

(July 1, 2021)

 United States US Healthcare US Biotechnology
464 Epizyme, Inc. $247.5 M

(Aug. 1, 2022)

 United States US Healthcare US Biotechnology
465 Hamilton Thorne Ltd $246.4 M

(Dec. 1, 2024)

 United States US Healthcare US Medical Devices
466 Nautilus Biotechnology, Inc. $241.2 M United States US Healthcare US Biotechnology
467 Senseonics Holdings, Inc. $240.7 M United States US Healthcare US Diagnostics & Research
468 Armata Pharmaceuticals Inc. $238.8 M United States US Healthcare US Biotechnology
469 Tabula Rasa HealthCare, Inc. $237.2 M

(July 1, 2023)

 United States US Healthcare US Health Information Services
470 Inhibikase Therapeutics, Inc. $236.5 M United States US Healthcare US Biotechnology
471 Shattuck Labs, Inc. $234.8 M United States US Healthcare US Biotechnology
472 OptimizeRx Corporation $231.5 M United States US Healthcare US Health Information Services
473 Checkmate Pharmaceuticals, Inc. $231.4 M

(May 1, 2022)

 United States US Healthcare US Biotechnology
474 Heron Therapeutics, Inc. $231.0 M United States US Healthcare US Biotechnology
475 Electromed, Inc. $229.4 M United States US Healthcare US Medical Devices
476 IntriCon Corporation $225.5 M

(May 1, 2022)

 United States US Healthcare US Medical Instruments & Supplies
477 Voyager Therapeutics, Inc. $224.1 M United States US Healthcare US Biotechnology
478 Owens & Minor, Inc. $216.6 M United States US Healthcare US Medical Distribution
479 Stereotaxis, Inc. $216.5 M United States US Healthcare US Medical Instruments & Supplies
480 Capital Senior Living Corporation $216.1 M

(March 1, 2022)

 United States US Healthcare US Medical Care Facilities

Top Healthcare Companies from the United States as of Jan. 01, 2026

451. Aldeyra Therapeutics, Inc.

Company Profile: Aldeyra Therapeutics, Inc.
Market Cap (USD): $281.0 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

452. Viemed Healthcare, Inc.

Company Profile: Viemed Healthcare, Inc.
Market Cap (USD): $280.0 M
Country: United States
Sector: US Healthcare
Industry: US Medical Devices

453. agilon health, Inc.

Company Profile: agilon health, Inc.
Market Cap (USD): $279.3 M
Country: United States
Sector: US Healthcare
Industry: US Medical Care Facilities

454. Frontage Holdings Corp

Company Profile: Frontage Holdings Corp
Market Cap (USD): $276.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

455. Atea Pharmaceuticals, Inc.

Company Profile: Atea Pharmaceuticals, Inc.
Market Cap (USD): $271.9 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

456. SmileDirectClub, Inc.

Company Profile: SmileDirectClub, Inc.
Market Cap (USD): $270.7 M (July 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Medical Devices

457. Greenwich LifeSciences, Inc.

Company Profile: Greenwich LifeSciences, Inc.
Market Cap (USD): $269.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

458. Fennec Pharmaceuticals Inc.

Company Profile: Fennec Pharmaceuticals Inc.
Market Cap (USD): $262.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

459. Galectin Therapeutics, Inc.

Company Profile: Galectin Therapeutics, Inc.
Market Cap (USD): $261.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

460. Repro Med Systems, Inc.

Company Profile: Repro Med Systems, Inc.
Market Cap (USD): $259.9 M
Country: United States
Sector: US Healthcare
Industry: US Medical Instruments & Supplies

461. Inozyme Pharma, Inc.

Company Profile: Inozyme Pharma, Inc.
Market Cap (USD): $258.2 M (July 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

462. Vor Biopharma, Inc.

Company Profile: Vor Biopharma, Inc.
Market Cap (USD): $255.0 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

463. Chiasma, Inc.

Company Profile: Chiasma, Inc.
Market Cap (USD): $253.0 M (July 1, 2021)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

464. Epizyme, Inc.

Company Profile: Epizyme, Inc.
Market Cap (USD): $247.5 M (Aug. 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

465. Hamilton Thorne Ltd

Company Profile: Hamilton Thorne Ltd
Market Cap (USD): $246.4 M (Dec. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Medical Devices

466. Nautilus Biotechnology, Inc.

Company Profile: Nautilus Biotechnology, Inc.
Market Cap (USD): $241.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

467. Senseonics Holdings, Inc.

Company Profile: Senseonics Holdings, Inc.
Market Cap (USD): $240.7 M
Country: United States
Sector: US Healthcare
Industry: US Diagnostics & Research

468. Armata Pharmaceuticals Inc.

Company Profile: Armata Pharmaceuticals Inc.
Market Cap (USD): $238.8 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

469. Tabula Rasa HealthCare, Inc.

Company Profile: Tabula Rasa HealthCare, Inc.
Market Cap (USD): $237.2 M (July 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Health Information Services

470. Inhibikase Therapeutics, Inc.

Company Profile: Inhibikase Therapeutics, Inc.
Market Cap (USD): $236.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

471. Shattuck Labs, Inc.

Company Profile: Shattuck Labs, Inc.
Market Cap (USD): $234.8 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

472. OptimizeRx Corporation

Company Profile: OptimizeRx Corporation
Market Cap (USD): $231.5 M
Country: United States
Sector: US Healthcare
Industry: US Health Information Services

473. Checkmate Pharmaceuticals, Inc.

Company Profile: Checkmate Pharmaceuticals, Inc.
Market Cap (USD): $231.4 M (May 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

474. Heron Therapeutics, Inc.

Company Profile: Heron Therapeutics, Inc.
Market Cap (USD): $231.0 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

475. Electromed, Inc.

Company Profile: Electromed, Inc.
Market Cap (USD): $229.4 M
Country: United States
Sector: US Healthcare
Industry: US Medical Devices

476. IntriCon Corporation

Company Profile: IntriCon Corporation
Market Cap (USD): $225.5 M (May 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Medical Instruments & Supplies

477. Voyager Therapeutics, Inc.

Company Profile: Voyager Therapeutics, Inc.
Market Cap (USD): $224.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

478. Owens & Minor, Inc.

Company Profile: Owens & Minor, Inc.
Market Cap (USD): $216.6 M
Country: United States
Sector: US Healthcare
Industry: US Medical Distribution

479. Stereotaxis, Inc.

Company Profile: Stereotaxis, Inc.
Market Cap (USD): $216.5 M
Country: United States
Sector: US Healthcare
Industry: US Medical Instruments & Supplies

480. Capital Senior Living Corporation

Company Profile: Capital Senior Living Corporation
Market Cap (USD): $216.1 M (March 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Medical Care Facilities

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