United States

Top 1000 largest US Companies in the Healthcare sector by Market Cap

This is the list of the largest public listed companies in the Healthcare sector from the United States by market capitalization with links to their reference stock and industry.

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Top Healthcare Companies from the United States as of Jan. 01, 2026

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Rank Company Market Cap (USD) Country Sector Industry
421 Cerus Corporation $378.4 M United States US Healthcare US Biotechnology
422 Lineage Cell Therapeutics, Inc. $377.7 M United States US Healthcare US Biotechnology
423 Rocket Pharmaceuticals, Inc. $374.4 M United States US Healthcare US Biotechnology
424 Palisade Bio, Inc. $373.0 M United States US Healthcare US Biotechnology
425 Adamas Pharmaceuticals, Inc. $371.8 M

(Nov. 1, 2021)

 United States US Healthcare US Drug Manufacturers—Specialty & Generic
426 Altimmune, Inc. $366.2 M United States US Healthcare US Biotechnology
427 AzurRx BioPharma, Inc. $366.2 M United States US Healthcare US Biotechnology
428 Simulations Plus, Inc. $364.8 M United States US Healthcare US Health Information Services
429 SeaSpine Holdings Corporation $360.2 M

(Jan. 1, 2023)

 United States US Healthcare US Medical Devices
430 Chimerix, Inc. $356.3 M

(Jan. 1, 2025)

 United States US Healthcare US Biotechnology
431 Delcath Systems, Inc. $351.4 M United States US Healthcare US Medical Devices
432 XOMA Corporation $346.6 M United States US Healthcare US Biotechnology
433 Silverback Therapeutics, Inc. $341.8 M

(July 1, 2024)

 United States US Healthcare US Biotechnology
434 CytoDyn, Inc. $341.8 M United States US Healthcare US Biotechnology
435 X4 Pharmaceuticals, Inc. $340.1 M United States US Healthcare US Biotechnology
436 Castlight Health, Inc. $335.5 M

(Feb. 1, 2022)

 United States US Healthcare US Health Information Services
437 Anavex Life Sciences Corp. $328.8 M United States US Healthcare US Biotechnology
438 Relmada Therapeutics, Inc. $320.5 M United States US Healthcare US Drug Manufacturers—Specialty & Generic
439 Aclaris Therapeutics, Inc. $312.0 M United States US Healthcare US Biotechnology
440 Allogene Therapeutics, Inc. $303.4 M United States US Healthcare US Biotechnology
441 Computer Programs and Systems, Inc. $303.2 M United States US Healthcare US Health Information Services
442 Quanterix Corporation $300.4 M United States US Healthcare US Medical Devices
443 Oyster Point Pharma, Inc. $299.9 M

(Dec. 1, 2022)

 United States US Healthcare US Biotechnology
444 Larimar Therapeutics, Inc. $297.0 M United States US Healthcare US Biotechnology
445 SOC Telemed, Inc. $295.7 M

(April 1, 2022)

 United States US Healthcare US Medical Care Facilities
446 Foghorn Therapeutics Inc. $293.5 M United States US Healthcare US Biotechnology
447 Puma Biotechnology, Inc. $290.8 M United States US Healthcare US Biotechnology
448 Alimera Sciences, Inc. $290.8 M

(July 1, 2024)

 United States US Healthcare US Drug Manufacturers—Specialty & Generic
449 Abeona Therapeutics Inc. $287.8 M United States US Healthcare US Biotechnology
450 Cerecor Inc. $285.0 M

(June 1, 2022)

 United States US Healthcare US Biotechnology

Top Healthcare Companies from the United States as of Jan. 01, 2026

421. Cerus Corporation

Company Profile: Cerus Corporation
Market Cap (USD): $378.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

422. Lineage Cell Therapeutics, Inc.

Company Profile: Lineage Cell Therapeutics, Inc.
Market Cap (USD): $377.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

423. Rocket Pharmaceuticals, Inc.

Company Profile: Rocket Pharmaceuticals, Inc.
Market Cap (USD): $374.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

424. Palisade Bio, Inc.

Company Profile: Palisade Bio, Inc.
Market Cap (USD): $373.0 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

425. Adamas Pharmaceuticals, Inc.

Company Profile: Adamas Pharmaceuticals, Inc.
Market Cap (USD): $371.8 M (Nov. 1, 2021)
Country: United States
Sector: US Healthcare
Industry: US Drug Manufacturers—Specialty & Generic

426. Altimmune, Inc.

Company Profile: Altimmune, Inc.
Market Cap (USD): $366.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

427. AzurRx BioPharma, Inc.

Company Profile: AzurRx BioPharma, Inc.
Market Cap (USD): $366.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

428. Simulations Plus, Inc.

Company Profile: Simulations Plus, Inc.
Market Cap (USD): $364.8 M
Country: United States
Sector: US Healthcare
Industry: US Health Information Services

429. SeaSpine Holdings Corporation

Company Profile: SeaSpine Holdings Corporation
Market Cap (USD): $360.2 M (Jan. 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Medical Devices

430. Chimerix, Inc.

Company Profile: Chimerix, Inc.
Market Cap (USD): $356.3 M (Jan. 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

431. Delcath Systems, Inc.

Company Profile: Delcath Systems, Inc.
Market Cap (USD): $351.4 M
Country: United States
Sector: US Healthcare
Industry: US Medical Devices

432. XOMA Corporation

Company Profile: XOMA Corporation
Market Cap (USD): $346.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

433. Silverback Therapeutics, Inc.

Company Profile: Silverback Therapeutics, Inc.
Market Cap (USD): $341.8 M (July 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

434. CytoDyn, Inc.

Company Profile: CytoDyn, Inc.
Market Cap (USD): $341.8 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

435. X4 Pharmaceuticals, Inc.

Company Profile: X4 Pharmaceuticals, Inc.
Market Cap (USD): $340.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

436. Castlight Health, Inc.

Company Profile: Castlight Health, Inc.
Market Cap (USD): $335.5 M (Feb. 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Health Information Services

437. Anavex Life Sciences Corp.

Company Profile: Anavex Life Sciences Corp.
Market Cap (USD): $328.8 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

438. Relmada Therapeutics, Inc.

Company Profile: Relmada Therapeutics, Inc.
Market Cap (USD): $320.5 M
Country: United States
Sector: US Healthcare
Industry: US Drug Manufacturers—Specialty & Generic

439. Aclaris Therapeutics, Inc.

Company Profile: Aclaris Therapeutics, Inc.
Market Cap (USD): $312.0 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

440. Allogene Therapeutics, Inc.

Company Profile: Allogene Therapeutics, Inc.
Market Cap (USD): $303.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

441. Computer Programs and Systems, Inc.

Company Profile: Computer Programs and Systems, Inc.
Market Cap (USD): $303.2 M
Country: United States
Sector: US Healthcare
Industry: US Health Information Services

442. Quanterix Corporation

Company Profile: Quanterix Corporation
Market Cap (USD): $300.4 M
Country: United States
Sector: US Healthcare
Industry: US Medical Devices

443. Oyster Point Pharma, Inc.

Company Profile: Oyster Point Pharma, Inc.
Market Cap (USD): $299.9 M (Dec. 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

444. Larimar Therapeutics, Inc.

Company Profile: Larimar Therapeutics, Inc.
Market Cap (USD): $297.0 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

445. SOC Telemed, Inc.

Company Profile: SOC Telemed, Inc.
Market Cap (USD): $295.7 M (April 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Medical Care Facilities

446. Foghorn Therapeutics Inc.

Company Profile: Foghorn Therapeutics Inc.
Market Cap (USD): $293.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

447. Puma Biotechnology, Inc.

Company Profile: Puma Biotechnology, Inc.
Market Cap (USD): $290.8 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

448. Alimera Sciences, Inc.

Company Profile: Alimera Sciences, Inc.
Market Cap (USD): $290.8 M (July 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Drug Manufacturers—Specialty & Generic

449. Abeona Therapeutics Inc.

Company Profile: Abeona Therapeutics Inc.
Market Cap (USD): $287.8 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

450. Cerecor Inc.

Company Profile: Cerecor Inc.
Market Cap (USD): $285.0 M (June 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

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