United States

Top 1000 largest US Companies in the Healthcare sector by Market Cap

This is the list of the largest public listed companies in the Healthcare sector from the United States by market capitalization with links to their reference stock and industry.

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Top Healthcare Companies from the United States as of Jul. 01, 2025

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Rank Company Market Cap (USD) Country Sector Industry
511 Black Diamond Therapeutics, Inc. $146.7 M United States US Healthcare US Biotechnology
512 Cabaletta Bio, Inc. $146.6 M United States US Healthcare US Biotechnology
513 Checkpoint Therapeutics, Inc. $146.5 M

(Jan. 1, 2025)

 United States US Healthcare US Biotechnology
514 Accuray Incorporated $146.3 M United States US Healthcare US Medical Devices
515 Lyell Immunopharma, Inc. $143.5 M United States US Healthcare US Biotechnology
516 AVITA Medical, Inc. $143.3 M United States US Healthcare US Medical Devices
517 Inhibikase Therapeutics, Inc. $140.5 M United States US Healthcare US Biotechnology
518 Assembly Biosciences, Inc. $138.5 M United States US Healthcare US Biotechnology
519 Galectin Therapeutics, Inc. $138.0 M United States US Healthcare US Biotechnology
520 Talaris Therapeutics, Inc. $137.4 M

(July 1, 2023)

 United States US Healthcare US Biotechnology
521 Strongbridge Biopharma plc $135.7 M

(Oct. 1, 2021)

 United States US Healthcare US Biotechnology
522 Selecta Biosciences, Inc. $135.2 M

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology
523 American Well Corporation $134.5 M United States US Healthcare US Health Information Services
524 Greenwich LifeSciences, Inc. $134.1 M United States US Healthcare US Biotechnology
525 Planet 13 Holdings, Inc. $133.9 M

(July 1, 2023)

 United States US Healthcare US Drug Manufacturers—Specialty & Generic
526 Seer, Inc. $133.6 M United States US Healthcare US Biotechnology
527 Computer Programs and Systems, Inc. $133.3 M United States US Healthcare US Health Information Services
528 RAPT Therapeutics, Inc. $133.1 M United States US Healthcare US Biotechnology
529 G1 Therapeutics, Inc. $131.2 M

(July 1, 2024)

 United States US Healthcare US Biotechnology
530 aTyr Pharma, Inc. $131.1 M United States US Healthcare US Biotechnology
531 Sangamo Therapeutics, Inc. $129.3 M United States US Healthcare US Biotechnology
532 InfuSystem Holdings Inc. $129.2 M United States US Healthcare US Medical Instruments & Supplies
533 Fate Therapeutics, Inc. $128.4 M United States US Healthcare US Biotechnology
534 Sesen Bio, Inc. $128.0 M

(March 1, 2023)

 United States US Healthcare US Biotechnology
535 Paratek Pharmaceuticals, Inc. $125.7 M

(July 1, 2023)

 United States US Healthcare US Biotechnology
536 Nkarta, Inc. $124.2 M United States US Healthcare US Biotechnology
537 Ironwood Pharmaceuticals, Inc. $124.0 M United States US Healthcare US Drug Manufacturers—Specialty & Generic
538 Graybug Vision, Inc. $121.0 M

(May 1, 2023)

 United States US Healthcare US Biotechnology
539 Progenity, Inc. $120.7 M

(July 1, 2024)

 United States US Healthcare US Biotechnology
540 Kinnate Biopharma Inc. $113.5 M

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology

Top Healthcare Companies from the United States as of Jul. 01, 2025

511. Black Diamond Therapeutics, Inc.

Company Profile: Black Diamond Therapeutics, Inc.
Market Cap (USD): $146.7 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

512. Cabaletta Bio, Inc.

Company Profile: Cabaletta Bio, Inc.
Market Cap (USD): $146.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

513. Checkpoint Therapeutics, Inc.

Company Profile: Checkpoint Therapeutics, Inc.
Market Cap (USD): $146.5 M (Jan. 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

514. Accuray Incorporated

Company Profile: Accuray Incorporated
Market Cap (USD): $146.3 M
Country: United States
Sector: US Healthcare
Industry: US Medical Devices

515. Lyell Immunopharma, Inc.

Company Profile: Lyell Immunopharma, Inc.
Market Cap (USD): $143.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

516. AVITA Medical, Inc.

Company Profile: AVITA Medical, Inc.
Market Cap (USD): $143.3 M
Country: United States
Sector: US Healthcare
Industry: US Medical Devices

517. Inhibikase Therapeutics, Inc.

Company Profile: Inhibikase Therapeutics, Inc.
Market Cap (USD): $140.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

518. Assembly Biosciences, Inc.

Company Profile: Assembly Biosciences, Inc.
Market Cap (USD): $138.5 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

519. Galectin Therapeutics, Inc.

Company Profile: Galectin Therapeutics, Inc.
Market Cap (USD): $138.0 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

520. Talaris Therapeutics, Inc.

Company Profile: Talaris Therapeutics, Inc.
Market Cap (USD): $137.4 M (July 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

521. Strongbridge Biopharma plc

Company Profile: Strongbridge Biopharma plc
Market Cap (USD): $135.7 M (Oct. 1, 2021)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

522. Selecta Biosciences, Inc.

Company Profile: Selecta Biosciences, Inc.
Market Cap (USD): $135.2 M (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

523. American Well Corporation

Company Profile: American Well Corporation
Market Cap (USD): $134.5 M
Country: United States
Sector: US Healthcare
Industry: US Health Information Services

524. Greenwich LifeSciences, Inc.

Company Profile: Greenwich LifeSciences, Inc.
Market Cap (USD): $134.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

525. Planet 13 Holdings, Inc.

Company Profile: Planet 13 Holdings, Inc.
Market Cap (USD): $133.9 M (July 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Drug Manufacturers—Specialty & Generic

526. Seer, Inc.

Company Profile: Seer, Inc.
Market Cap (USD): $133.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

527. Computer Programs and Systems, Inc.

Company Profile: Computer Programs and Systems, Inc.
Market Cap (USD): $133.3 M
Country: United States
Sector: US Healthcare
Industry: US Health Information Services

528. RAPT Therapeutics, Inc.

Company Profile: RAPT Therapeutics, Inc.
Market Cap (USD): $133.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

529. G1 Therapeutics, Inc.

Company Profile: G1 Therapeutics, Inc.
Market Cap (USD): $131.2 M (July 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

530. aTyr Pharma, Inc.

Company Profile: aTyr Pharma, Inc.
Market Cap (USD): $131.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

531. Sangamo Therapeutics, Inc.

Company Profile: Sangamo Therapeutics, Inc.
Market Cap (USD): $129.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

532. InfuSystem Holdings Inc.

Company Profile: InfuSystem Holdings Inc.
Market Cap (USD): $129.2 M
Country: United States
Sector: US Healthcare
Industry: US Medical Instruments & Supplies

533. Fate Therapeutics, Inc.

Company Profile: Fate Therapeutics, Inc.
Market Cap (USD): $128.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

534. Sesen Bio, Inc.

Company Profile: Sesen Bio, Inc.
Market Cap (USD): $128.0 M (March 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

535. Paratek Pharmaceuticals, Inc.

Company Profile: Paratek Pharmaceuticals, Inc.
Market Cap (USD): $125.7 M (July 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

536. Nkarta, Inc.

Company Profile: Nkarta, Inc.
Market Cap (USD): $124.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

537. Ironwood Pharmaceuticals, Inc.

Company Profile: Ironwood Pharmaceuticals, Inc.
Market Cap (USD): $124.0 M
Country: United States
Sector: US Healthcare
Industry: US Drug Manufacturers—Specialty & Generic

538. Graybug Vision, Inc.

Company Profile: Graybug Vision, Inc.
Market Cap (USD): $121.0 M (May 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

539. Progenity, Inc.

Company Profile: Progenity, Inc.
Market Cap (USD): $120.7 M (July 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

540. Kinnate Biopharma Inc.

Company Profile: Kinnate Biopharma Inc.
Market Cap (USD): $113.5 M (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

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