United States

Top 1000 largest US Companies in the Healthcare sector by Market Cap

This is the list of the largest public listed companies in the Healthcare sector from the United States by market capitalization with links to their reference stock and industry.

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Top Healthcare Companies from the United States as of Jan. 01, 2026

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Rank Company Market Cap (USD) Country Sector Industry
511 Health Catalyst, Inc. $161.3 M United States US Healthcare US Health Information Services
512 Treace Medical Concepts, Inc. $159.3 M United States US Healthcare US Medical Devices
513 La Jolla Pharmaceutical Company $155.1 M

(Aug. 1, 2022)

 United States US Healthcare US Biotechnology
514 Invitae Corporation $147.7 M

(Jan. 1, 2024)

 United States US Healthcare US Diagnostics & Research
515 Sangamo Therapeutics, Inc. $147.6 M United States US Healthcare US Biotechnology
516 Checkpoint Therapeutics, Inc. $146.5 M

(Jan. 1, 2025)

 United States US Healthcare US Biotechnology
517 Codexis, Inc. $145.4 M United States US Healthcare US Biotechnology
518 Mersana Therapeutics, Inc. $145.2 M United States US Healthcare US Biotechnology
519 Black Diamond Therapeutics, Inc. $141.9 M United States US Healthcare US Biotechnology
520 LENSAR, Inc. $138.7 M United States US Healthcare US Medical Devices
521 Talaris Therapeutics, Inc. $137.4 M

(July 1, 2023)

 United States US Healthcare US Biotechnology
522 Seres Therapeutics, Inc. $137.1 M United States US Healthcare US Biotechnology
523 Strongbridge Biopharma plc $135.7 M

(Oct. 1, 2021)

 United States US Healthcare US Biotechnology
524 Selecta Biosciences, Inc. $135.2 M

(Jan. 1, 2024)

 United States US Healthcare US Biotechnology
525 Anika Therapeutics, Inc. $134.8 M United States US Healthcare US Biotechnology
526 The Joint Corp. $134.4 M United States US Healthcare US Medical Care Facilities
527 Planet 13 Holdings, Inc. $133.9 M

(July 1, 2023)

 United States US Healthcare US Drug Manufacturers—Specialty & Generic
528 Nkarta, Inc. $132.8 M United States US Healthcare US Biotechnology
529 Spero Therapeutics, Inc. $132.4 M United States US Healthcare US Biotechnology
530 G1 Therapeutics, Inc. $131.2 M

(July 1, 2024)

 United States US Healthcare US Biotechnology
531 Sesen Bio, Inc. $128.0 M

(March 1, 2023)

 United States US Healthcare US Biotechnology
532 Paratek Pharmaceuticals, Inc. $125.7 M

(July 1, 2023)

 United States US Healthcare US Biotechnology
533 Ovid Therapeutics Inc. $125.3 M United States US Healthcare US Biotechnology
534 Fortress Biotech, Inc. $125.1 M United States US Healthcare US Biotechnology
535 Pro-Dex, Inc. $123.7 M United States US Healthcare US Medical Instruments & Supplies
536 Karyopharm Therapeutics Inc. $122.6 M United States US Healthcare US Biotechnology
537 Eledon Pharmaceuticals, Inc. $121.6 M United States US Healthcare US Biotechnology
538 Graybug Vision, Inc. $121.0 M

(May 1, 2023)

 United States US Healthcare US Biotechnology
539 Progenity, Inc. $120.7 M

(July 1, 2024)

 United States US Healthcare US Biotechnology
540 Avalon GloboCare Corp. $119.1 M United States US Healthcare US Medical Care Facilities

Top Healthcare Companies from the United States as of Jan. 01, 2026

511. Health Catalyst, Inc.

Company Profile: Health Catalyst, Inc.
Market Cap (USD): $161.3 M
Country: United States
Sector: US Healthcare
Industry: US Health Information Services

512. Treace Medical Concepts, Inc.

Company Profile: Treace Medical Concepts, Inc.
Market Cap (USD): $159.3 M
Country: United States
Sector: US Healthcare
Industry: US Medical Devices

513. La Jolla Pharmaceutical Company

Company Profile: La Jolla Pharmaceutical Company
Market Cap (USD): $155.1 M (Aug. 1, 2022)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

514. Invitae Corporation

Company Profile: Invitae Corporation
Market Cap (USD): $147.7 M (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Diagnostics & Research

515. Sangamo Therapeutics, Inc.

Company Profile: Sangamo Therapeutics, Inc.
Market Cap (USD): $147.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

516. Checkpoint Therapeutics, Inc.

Company Profile: Checkpoint Therapeutics, Inc.
Market Cap (USD): $146.5 M (Jan. 1, 2025)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

517. Codexis, Inc.

Company Profile: Codexis, Inc.
Market Cap (USD): $145.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

518. Mersana Therapeutics, Inc.

Company Profile: Mersana Therapeutics, Inc.
Market Cap (USD): $145.2 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

519. Black Diamond Therapeutics, Inc.

Company Profile: Black Diamond Therapeutics, Inc.
Market Cap (USD): $141.9 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

520. LENSAR, Inc.

Company Profile: LENSAR, Inc.
Market Cap (USD): $138.7 M
Country: United States
Sector: US Healthcare
Industry: US Medical Devices

521. Talaris Therapeutics, Inc.

Company Profile: Talaris Therapeutics, Inc.
Market Cap (USD): $137.4 M (July 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

522. Seres Therapeutics, Inc.

Company Profile: Seres Therapeutics, Inc.
Market Cap (USD): $137.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

523. Strongbridge Biopharma plc

Company Profile: Strongbridge Biopharma plc
Market Cap (USD): $135.7 M (Oct. 1, 2021)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

524. Selecta Biosciences, Inc.

Company Profile: Selecta Biosciences, Inc.
Market Cap (USD): $135.2 M (Jan. 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

525. Anika Therapeutics, Inc.

Company Profile: Anika Therapeutics, Inc.
Market Cap (USD): $134.8 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

526. The Joint Corp.

Company Profile: The Joint Corp.
Market Cap (USD): $134.4 M
Country: United States
Sector: US Healthcare
Industry: US Medical Care Facilities

527. Planet 13 Holdings, Inc.

Company Profile: Planet 13 Holdings, Inc.
Market Cap (USD): $133.9 M (July 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Drug Manufacturers—Specialty & Generic

528. Nkarta, Inc.

Company Profile: Nkarta, Inc.
Market Cap (USD): $132.8 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

529. Spero Therapeutics, Inc.

Company Profile: Spero Therapeutics, Inc.
Market Cap (USD): $132.4 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

530. G1 Therapeutics, Inc.

Company Profile: G1 Therapeutics, Inc.
Market Cap (USD): $131.2 M (July 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

531. Sesen Bio, Inc.

Company Profile: Sesen Bio, Inc.
Market Cap (USD): $128.0 M (March 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

532. Paratek Pharmaceuticals, Inc.

Company Profile: Paratek Pharmaceuticals, Inc.
Market Cap (USD): $125.7 M (July 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

533. Ovid Therapeutics Inc.

Company Profile: Ovid Therapeutics Inc.
Market Cap (USD): $125.3 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

534. Fortress Biotech, Inc.

Company Profile: Fortress Biotech, Inc.
Market Cap (USD): $125.1 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

535. Pro-Dex, Inc.

Company Profile: Pro-Dex, Inc.
Market Cap (USD): $123.7 M
Country: United States
Sector: US Healthcare
Industry: US Medical Instruments & Supplies

536. Karyopharm Therapeutics Inc.

Company Profile: Karyopharm Therapeutics Inc.
Market Cap (USD): $122.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

537. Eledon Pharmaceuticals, Inc.

Company Profile: Eledon Pharmaceuticals, Inc.
Market Cap (USD): $121.6 M
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

538. Graybug Vision, Inc.

Company Profile: Graybug Vision, Inc.
Market Cap (USD): $121.0 M (May 1, 2023)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

539. Progenity, Inc.

Company Profile: Progenity, Inc.
Market Cap (USD): $120.7 M (July 1, 2024)
Country: United States
Sector: US Healthcare
Industry: US Biotechnology

540. Avalon GloboCare Corp.

Company Profile: Avalon GloboCare Corp.
Market Cap (USD): $119.1 M
Country: United States
Sector: US Healthcare
Industry: US Medical Care Facilities

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